Results 41 to 50 of about 32,583,175 (200)
Images of formal matrices of elements of matrix groups over associative rings
, 2020 The paper substantiates the image by formal matrices of some elements of linear groups over associative rings by using the properties of redundant and fixed modules.
Ю. В. Петечук +1 more
core +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Projective modules of group rings over quadratic number fields [PDF]
, 1994 Let K be a quadratic number field, Ok its ring of integers, and G a cyclic group of order prime p. In this thesis, we study the kernel group D(O(_K)G) and obtain a number of results concerning its order and structure. For K imaginary, we also investigate
Ahmed, Iftikhar
core
Kimmerle conjecture for the Held and O'Nan sporadic simple groups [PDF]
, 2009 Using the Luthar--Passi method, we investigate the Zassenhaus and Kimmerle conjectures for normalized unit groups of integral group rings of the Held and O'Nan sporadic simple groups.
Bódi, Viktor +2 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Isomorphisms of matrix groups over commutative rings
, 2017 http://pub.acta.hu/acta/showCustomerVolume.action?id=48928&dataObjectType=volume&noDataSet=true&style=Abstract. We give a description of the isomorphism classes of matrix groups over commutative rings with 1 and that have dimension more than 3 and ...
Петечук Юлія +5 more
core +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source