Results 131 to 140 of about 490,864 (295)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Robust motion planning for autonomous tracked vehicles in deformable terrain [PDF]
, 2016 Thesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2016.Cataloged from PDF version of thesis.Includes bibliographical references (pages 90-95).Ensuring the safety of autonomous vehicles during operation is a ...
Lee, Sang Uk, (Scientist in Mechanical Engineering), author.
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Some trends in the career paths followed by alumni of the MIT Mechanical Engineering Department [PDF]
, 2003 Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2003.Includes bibliographical references.Data was collected in order to determine the career paths followed by graduates of MIT's mechanical engineering department ...
Kelly, Catherine A. (Catherine Ann), 1981-
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Getting to gender parity in the Mechanical Engineering Department at MIT [PDF]
, 2016 Thesis: S.B., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2016.Cataloged from PDF version of thesis.Includes bibliographical references (pages 90-95).Consistently ranked as home to one of the world's top engineering ...
Xu, Kathleen L
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Model-free tracking control of an optical fiber drawing process using deep reinforcement learning [PDF]
, 2020 Thesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, May, 2020Cataloged from the PDF version of thesis.Includes bibliographical references (pages 73-76).A deep reinforcement learning (DRL) approach for tracking ...
Kim, Sangwoon, (Mechanical engineer) Massachusetts Institute of Technology.
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Nonlinear Partial Differential Equations Analysis in all Engineering Fields (Chemical, Mechanical, Civil, Electrical and other fields) and Basic Sciences by new Approach ASM [PDF]
Archives in Biomedical Engineering & Biotechnology, 2021 openaire +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source