Results 41 to 50 of about 439,302 (251)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Journal of Information Science Theory and Practice, 2017 This study examined the mechanical engineering research output from India, Japan, and South Korea on different parameters including growth, collaboration indices, and activity index.
Pattanashetti, D.M., Harinarayana, N.S.
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Agrointek, 2021 The physical and mechanical properties of the material to be processed are fundamental and continue to be a challenge for researchers to design a machine appropriately.
Agustami Sitorus +2 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The status of technology development in Iran with a look at the condition of mechanical engineering
آموزش مهندسی ایران, 2020 Today, technology development is not only a straight forward approach to create wealth, but is a means for superiority of countries in military, industry and economy.
Alli Ghafari +1 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A Damaged Constitutive Model for Rock under Dynamic and High Stress State
Shock and Vibration, 2017 The main research work of this paper focuses on the theoretical prediction of the constitutive relationship for rock, concrete, and other quasi-brittle materials under dynamic and complex stress state and the influence of dynamic mechanical behavior of ...
Yan-Long Li, Zong-Yuan Ma
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Advanced Science, 2021 Nano‐immunotherapy regimens have high potential to improve patient outcomes, as already demonstrated in advanced triple negative breast cancer with nanoparticle albumin‐bound paclitaxel and the immune checkpoint blocker (ICB) atezolizumab.
Fotios Mpekris +18 more
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