Results 51 to 60 of about 1,856,164 (287)
Advanced Science, 2021 Nano‐immunotherapy regimens have high potential to improve patient outcomes, as already demonstrated in advanced triple negative breast cancer with nanoparticle albumin‐bound paclitaxel and the immune checkpoint blocker (ICB) atezolizumab.
Fotios Mpekris +18 more
doaj +1 more source
Double-edged role of mechanical stimuli and underlying mechanisms in cartilage tissue engineering
Frontiers in Bioengineering and Biotechnology, 2023 Mechanical stimuli regulate the chondrogenic differentiation of mesenchymal stem cells and the homeostasis of chondrocytes, thus affecting implant success in cartilage tissue engineering.
Yao Jia +9 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The status of technology development in Iran with a look at the condition of mechanical engineering
آموزش مهندسی ایران, 2020 Today, technology development is not only a straight forward approach to create wealth, but is a means for superiority of countries in military, industry and economy.
Alli Ghafari +1 more
doaj +1 more source
U.Porto Journal of Engineering, 2021 This paper presents the reformulation of the Integrated Master in Mechanical Engineering (MIEM) at the Faculty of Engineering of the University of Porto (FEUP) in two independent degrees (bachelor and master).
Lucas da Silva +2 more
doaj +1 more source
Thermal and electronic transport characteristics of highly stretchable graphene kirigami
, 2017 For centuries, cutting and folding the papers with special patterns have been used to build beautiful, flexible and complex three-dimensional structures.
Charlier, Jean-Christophe +5 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
A Damaged Constitutive Model for Rock under Dynamic and High Stress State
Shock and Vibration, 2017 The main research work of this paper focuses on the theoretical prediction of the constitutive relationship for rock, concrete, and other quasi-brittle materials under dynamic and complex stress state and the influence of dynamic mechanical behavior of ...
Yan-Long Li, Zong-Yuan Ma
doaj +1 more source
Stochastic Resonance Can Drive Adaptive Physiological Processes [PDF]
, 2009 Stochastic resonance (SR) is a concept from the physics and engineering communities that has applicability to both systems physiology and other living systems. In this paper, it will be argued that stochastic resonance plays a role in driving behavior in
Bradly J. Alicea
core +1 more source