Results 141 to 150 of about 4,794,371 (307)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Challenges and Proposed Strategies for Enhancing the Comprehensive Program of Justice, Excellence, and Productivity in Medical Education: A case Study of Arak University of Medical Sciences [PDF]

Journal of Medical Education and Development
Introduction: The Comprehensive Program of justice, excellence, and productivity in Medical Education, as the most recent reform initiative in Iran’s higher health education system, is currently being implemented in Iranian medical sciences universities.
Mohanna Rajabi, raheleh soltani
doaj  

Presencia de revistas españolas en bases de datos internacionales [PDF]

, 2017
This chapter analyses the presence of Spanish scientific journals in the main international databases (Web of Science, Scopus, DOAJ and other multidisciplinary databases), with a special focus on distribution by subject matter.
Abadal, Ernest, Guallar, Javier, Rodríguez-Gairín, Josep-Manuel, Somoza, Marta   +3 more
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Facts and Assertiveness in the Direction of Elementary Skills Between Medicinal Apprentices Joined in Medical Eons in Cloistered Therapeutic Institutions

The International Journal of Frontier Sciences
Background: To make basic sciences easy and accessible to enhance their clinical importance. Objective: basic sciences in medical education have a pivotal role in forming foundation of a medical students.
Wajahat Hussain, Roomana Anwar, Muhammad Tariq Choudhry, Muhammad Arif Khan   +3 more
doaj   +1 more source

UPDATES!!! Eko University of Medical and Health Sciences Ijanikin, Lagos,2022/2023 Pre-Degree/ Jupeb/REMEDIAL Admission Form ☎" 0706_5086_538, ☎+23470-6508-6538 Prof Mrs ANITA 07065086538 the Degree Programme is 5 credits including English Language, Mathematics and any three other relevant subjects at the WASC/NECO/NABTEB Examinations or their equivalent (at not more than 2 sittings

, 2022
javvy
openalex   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Investigation of science production in Iran’s type I universities of medical sciences, a 6-year assessment

Journal of Health Management & Informatics, 2014
Introduction: Science production is one of the main dimensions of sustainable development in any country. Thus, universities as the major centers for science production play a key role in development.
M Yadollahi, N Shamsedini, N Haseli
doaj