Results 211 to 220 of about 4,774,812 (307)

A rare presentation of actinomycotic mycetoma of the hand: a case report. [PDF]

BMC Infect Dis
Layegh Mirhosseyni S, Abdi A, Kord M, Ahmadikia K, Alavi Darazam I.   +4 more
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Retraction: Investigation of the biological activity, mechanical properties and wound healing application of a novel scaffold based on lignin-agarose hydrogel and silk fibroin embedded zinc chromite nanoparticles. [PDF]

RSC Adv
Eivazzadeh-Keihan R, Moghim Aliabadi HA, Radinekiyan F, Sobhani M, Khalili F, Maleki A, Madanchi H, Mahdavi M, Shalan AE.   +8 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Beyond the 'Go-Live': why context matters in EHR implementations. [PDF]

BMJ Health Care Inform
Chih MY, Warren JL, Iqbal U, Sholokhova K, Li YJ.   +4 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Anxiety and depression and its correlates among undergraduate medical students in Nepal: A cross-sectional study. [PDF]

PLOS Ment Health
Gaihre M, Rana A, Niroula S, Sejuwal AK, Dhakal R, Adhikari A, Devkota S, Shrestha R.   +7 more
europepmc   +1 more source

Successful Treatment Of COVID-19 With Convalescent Plasma Therapy, Actemra, Dexamethasone, Remdesivir and Oxygen Therapy and Other Medical, Surgical Diseases Treatment with The Help of Medical Sciences

American Journal of Biomedical Science & Research, 2021
openaire   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Genomic characterisation of extensively drug-resistant Acinetobacter baumannii isolates from a tertiary hospital in Ghana. [PDF]

PLoS One
Ashley-Agbedor IE, Mahazu S, Kotey FCN, Amedior J, Adu B, Darko E, Kwao P, Dayie NTKD, Ablordey AS, Opintan JA.   +9 more
europepmc   +1 more source