Results 121 to 130 of about 3,457,278 (273)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Creating a center for global health at the University of Wisconsin-Madison. [PDF]

open access: yes, 2008
Globalization, migration, and widespread health disparities call for interdisciplinary approaches to improve health care at home and abroad. Health professions students are pursuing study abroad in increasing numbers, and universities are responding with
Baumann, Linda   +7 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Greater Philadelphia's Knowledge Industry: Leveraging the Region's Colleges and Universities in the New Economy [PDF]

open access: yes, 2000
This report documents Greater Philadelphia's current standing as a knowledge region, compares its performance over a series of key indicators to the largest American knowledge regions, identifies activities being undertaken around the country, and offers

core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Evaluating Interprofessional Education Readiness and Perceptions Among Health Professions Students

open access: yesAdvances in Medical Education and Practice
Nouf Sulaiman Alharbi,1– 3 Nourah Mohammed Alenazi,4 Alaa Althubaiti,2,5 Reem Alkahtani,2,3,6 Seema Nasser,2,3,7 Marwh Gassim Aldriwesh2,3,8 1Department of Medical Education, College of Medicine, King Saud bin Abdulaziz University for Health Sciences ...
Alharbi NS   +5 more
doaj  

2017 Commencement for Sidney Kimmel Medical College, Jefferson Graduate School of Biomedical Sciences, and Jefferson School of Population Health [PDF]

open access: yes, 2017
Processional Trumpet Voluntary, JOHN STANLEY The Jefferson Processional, BURLE MARX Organist, THE REVEREND R. BRUCE TODD Opening Proclamation RICHARD W. HEVNER, Chair, Board of Trustees, Thomas Jefferson University and Jefferson Health Presentation

core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

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