Results 11 to 20 of about 412 (87)
Innate Immunity and Microbial Recognition in Reproduction: From Barrier Defense to Maternal-Fetal Tolerance. [PDF]
FASEB JGraphical abstract illustrating the barrier defense–tolerance framework of reproductive innate immunity. Across the female and male reproductive tracts and the maternal–fetal interface, epithelial barriers, innate sensors, immune cells, and microbial signals are integrated to preserve reproductive homeostasis.
Rao X, Zou L, Yao Y, Liu C.
europepmc +2 more sources
Machine Learning of Personal Repertoires From Public T Cell Receptors. [PDF]
Immunol RevABSTRACT The T‐cell receptor (TCR) repertoire records an individual's immunological history, but most unique CDR3 sequences in any one person are private and uninformative about anyone else. A small subset, however, recurs predictably across unrelated donors.
Malca O, Zilberberg A, Efroni S.
europepmc +2 more sources
RNA-Binding Proteins: Function, Biological Mechanisms, and Therapeutic Opportunities. [PDF]
MedComm (2020)RNA‐binding proteins (RBPs) regulate RNA stability, localization, translation, and splicing through intrinsic binding domains and interactions with diverse cellular partners. Their competitive and cooperative networks shape disease‐related RNA programs, especially in cancer.
Li L, Yan X, Ji Q, Zhang H.
europepmc +2 more sources
Chemistry – A European Journal, EarlyView.Hydrogen‐release processes in silicon chemistry occur across a broad spectrum of systems, including crystalline silicon surfaces, nanoporous materials, Zintl phases, and molecular hydrides. This Review highlights how Si─H activation and H2 evolution are governed by structure, coordination environment, and dynamic access to reactive geometries, with ...
Robin Rothfelder, Jonathan O. Bauer
wiley +1 more source
iMetaMed, EarlyView.This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu +7 more
wiley +1 more source
Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley +1 more source
Quantization of Polaritons Confined in Dielectric Structures
Laser &Photonics Reviews, EarlyView.This study addresses the limitations of the Hopfield model of strong light‐matter coupling in the case of structured dieletrics. A method to derive quantum models in the polariton basis using Bogoliubov transformation and third quantization is introduced, demonstrating how to boost interaction strength and engineer nonlocal interactions for strongly ...
Amir Rahmani +4 more
wiley +1 more source
Small, EarlyView.This review charts the material evolution of bifunctional electrocatalysts for rechargeable lithium‐gas batteries. It highlights the journey from heteroatom‐doped, metal‐free carbon architectures to precision‐engineered carbon‐supported single‐atom sites. The discussion focuses on mechanistic insights into how these catalysts govern reversible O2, CO2,
Daming Ren +5 more
wiley +1 more source
Noûs, EarlyView.ABSTRACTProbabilism is the thesis that the degrees of belief of rational agents behave like Kolmogorovian probabilities. There are quite different lines of argument for probabilism in the literature, including Dutch book arguments, arguments based on representation theorems, and epistemic utility arguments. This paper focusses on the Dutch book line of
Nicholas J. J. Smith
wiley +1 more source
Quantifiers for a Modal Future
Philosophical Perspectives, EarlyView.ABSTRACT Future auxiliaries present a challenge to the classical analysis of modal expressions as existential or universal quantifiers over a contextually provided set of possible worlds: these expressions come with a distinct modal flavor, but their interaction with negation and the fact that future judgments come in degrees of confidence is ...
Malte Willer
wiley +1 more source