Results 111 to 120 of about 22,563,111 (293)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Combining Empirical and Physics-Based Models for Solar Wind Prediction

open access: yesUniverse
Solar wind modeling is classified into two main types: empirical models and physics-based models, each designed to forecast solar wind properties in various regions of the heliosphere.
Rob Johnson   +3 more
doaj   +1 more source

Search for new physics in events with same-sign dileptons and jets in pp collisions at ?s = 8 TeV

open access: yes, 2014
A search for new physics is performed based on events with jets and a pair of isolated, same-sign leptons. The results are obtained using a sample of proton-proton collision data collected by the CMS experiment at a centre-of-mass energy of 8 TeV at the ...
Physics Collaboration, CMS Collaboration
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Pendulums and Nonlinear Effects - Warning 4000 level physics [video]

open access: yes, 2015
NPS PhysicsIn-class Physics DemonstrationsDr.
Naval Postgraduate School Physics
core   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

The oblique parameters from arbitrary new fermions

open access: yesJournal of High Energy Physics
We compute the six oblique parameters S, T, U, V, W, X in a New Physics Model with an arbitrary number of new fermions, in arbitrary representations of SU(2) × U(1), and mixing arbitrarily among themselves.
F. Albergaria   +2 more
doaj   +1 more source

Parallels Between Models of Gyrotron Physics and Some Famous Equations Used in Other Scientific Fields

open access: yesApplied Sciences
In this integrative review paper, we explore the parallels between the physical models of gyrotrons and some equations used in diverse and broad scientific fields.
Svilen Sabchevski
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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