Results 91 to 100 of about 343,843 (272)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The Social–Sensory Interface: Category Interactions in Person Perception
Frontiers in Integrative Neuroscience, 2012 Research is increasingly challenging the claim that distinct sources of social information—such as sex, race, and emotion—are processed in discrete fashion. Instead, there appear to be functionally relevant interactions that occur. In the present article,
Jonathan eFreeman +3 more
doaj +1 more source
Use of video modeling to increase generalization of social play by children with autism [PDF]
, 2007 The use of video modeling to increase generalization of social play skills in children with autism is discussed. The possible reasons that have made this procedure so favorable among researchers and practitioners are explored.
Nikopoulos, C K
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
A comparative study between Kuwait’s Government and Private Sector Primary Schools in methods of teaching and pupils’ achievement in mathematics [PDF]
, 2012 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The study aimed at identify the aspects associated with teaching mathematics and students’ learning through The framework for the scientific and theoretical
Al-Duwaila, Abdulrahman
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
The Social Study administers a yearly core study questionnaire that captures essential socio-demographic, behavioral, and attitudinal information among all panel members.
The Social Study
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Testing Behavioral Public Economics Theories in the Laboratory [PDF]
"Behavioral economics", or the application of methods and evidence from other social sciences to economics, has increased greatly in significance in the last two decades.
James Alm
core
Terrorism and the Behavioral Sciences
, 2010 Terrorism has existed for millennia and is a phenomenon well-known to many parts of the world. Americans were forced to recognize this phenomenon, and our vulnerability to it, by two sets of events in 2001: the attacks on New York City and Washington, DC,
Schouten, Ronald, Ronald Schouten
core +1 more source