Results 41 to 50 of about 351,056 (229)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Adolescents' Digital Literacies in Flux: Intersections of Voice, Empowerment, and Practices

open access: yesJournal of Media Literacy Education, 2019
This article features a collaborative autoethnographic examination of three adolescent-researchers’ digital literacies. The participatory design punctuates the role of the adolescent-researchers as they explored their meaning-making practices.
Sandra Schamroth Abrams   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Disinformation awareness via SMS? Exploring a new modality for boosting adult media literacy

open access: yesJournal of Media Literacy Education
Given a rapidly evolving disinformation environment, many initiatives are currently being developed to counter the harmful impacts of disinformation. The aim of this study is to explore how an SMS intervention, as a hitherto untested modality for raising
Jannie Lilja   +4 more
doaj   +1 more source

Book Review: Teaching Climate Change to Adolescents: Reading, Writing, and Making a Difference

open access: yesJournal of Media Literacy Education, 2018
Teaching Climate Change to Adolescents: Reading, Writing, and Making a Difference, is a book for English language arts and media literacy teachers that provides abundant resources for educators wanting to incorporate climate change instruction into their
Antonio Lopez
doaj   +1 more source

Determining the feasibility of an online, media mediation program for parents to improve parent-child sexual health communication

open access: yesJournal of Media Literacy Education, 2020
Media Aware Parent is an interactive, web-based program designed to equip parents to communicate with their adolescent child about sexual health and media by enhancing parental communication and media mediation skills, as well as provide them with ...
Tracy M Scull   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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