Results 121 to 130 of about 4,293,443 (353)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Scientific project, Sciences Po | LIEPP laboratoire interdisciplinaire d'evaluation des politiques publiques or in english, interdisciplinary research center for the evaluation of public policies [PDF]
Sciences Po develops an interdisciplinary research program for the evaluation of public policies (in French: Laboratoire interdisciplinaire d’évaluation des politiques publiques, LIEPP), based on four founding units: Department of Economics, Centre de ...
Wasmer, Etienne, Woll, Cornelia
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Jurnal Sosiologi Reflektif, 2016 Modern social sciences, including sociology, believe that religion is outside the world of science. The growth of the sciences is characterized by their secular perspectives.
Husnul Muttaqin
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
La perspective d’une science sociale Sud/Sud
SociologiesThis critical text on the discourse of critical sociology of the social sciences in the societies of the Maghreb-Mashrek, deconstructs the myth of the decline of the human sciences in Arab societies and attempts to explain this constantly unhappy ...
Kamel Chachoua
doaj +1 more source
Causal Depth: Aspects of a Scientific Realist Approach to Causal Explanation contra Humean Empiricism [PDF]
The purpose of this note is to clarify how the idea of "causal depth" can play a role in finding the more "approximately true" explanation through causal comparisons.
Khan, Haider
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Policy Researchers and Policymakers: Never the Twain Shall Meet? [PDF]
The 1980s have seen the heavy emphasis on economic policymaking. As such, equal emphasis has also been bestowed to the substantial improvement on the principles of analysis and evaluation developed by economists and other social scientists.
Glover, David
core +2 more sources