Results 221 to 230 of about 4,293,443 (353)

The age of authenticity anxiety: Artificial intelligence and emerging questions for mental health. [PDF]

PLOS Ment Health
Brown AD.
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Clarifying the neural circuit mechanisms of spontaneous social behavior in macaques. [PDF]

Front Neural Circuits
Ninomiya T, Kaneko T, Ono Y, Kobayashi K, Isoda M.   +4 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Social determinants of vaccine hesitancy among the Lebanese parents: A cross-sectional Study. [PDF]

PLoS One
Awad R, Rahal M, Henieneh AM, Salameh P, Farah R, Cherfane M, Kotb R, Nakhoul D, Khadaj R, Habib N, Iskandar K.   +10 more
europepmc   +1 more source

On the Importance of Frailty in Social Science Theory (and other lessons of agent-based modeling)

, 2013
Paul E. Johnson
openalex   +1 more source

An Overview of Decision theory and Game Theory and Some of its Applications in Economics & Other Social Sciences

Sri Naren Chandra Boro
openalex   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Behavioural and Social Drivers (BeSD) of COVID-19 vaccination for children: A cross-sectional study of parental vaccine confidence and intent in Mysore, India. [PDF]

PLoS One
Muralidhar K, Ngaybe MGB, Pope B, Nanjaiah S, Coursey K, Jaykrishna P, Ningaiah N, Edwards TL, Edwards DRV, Madhivanan P, Somaiya D, Krupp K.   +11 more
europepmc   +1 more source

The Social Sciences between Importation and Reappropriation: Anthropology and other Disciplines

, 2020
Abdellah Hammoudi
openalex   +1 more source