Results 191 to 200 of about 3,661,970 (379)

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

'The Health-Secure Partnership': Study protocol for the development of a school- & community-based intervention for promoting healthy nutrition among rural adolescents in The Gambia. [PDF]

PLoS One
Jallow-Badjan H, Bagnall AM, Apekey TA, Tunkara Bah H, Crookes H, Janha RE, Kassama F, Njie H, Erikowa-Orighoye O, Senghore T, Zabula T, Maynard MJ, Health Secure Partnership consortium.   +12 more
europepmc   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

A Design Architecture for Decentralized and Provenance-Assisted eHealth Systems for Enhanced Personalized Medicine. [PDF]

J Pers Med
Sergio WL, Ströele V, Braga R.
europepmc   +1 more source

Report to Ministers from the Department of Health Steering Group on the Statutory Regulation of Practitioners of Acupuncture, Herbal Medicine, Traditional Chinese Medicine and Other Traditional Medicine Systems Practised in the UK.

, 2008
This report represents a significant milestone in meeting the Government's objectives for the public safely to access acupuncture, herbal/traditional medicine and traditional Chinese medicine. It represents the culmination of many years of work by practitioners, the Prince's Foundation for Integrated Health (PFIH) and the Department of Health in ...
openaire   +1 more source

The relevance and potential roles of microphysiological systems in biology and medicine

Experimental biology and medicine, 2014
J. Wikswo
semanticscholar   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Three-Dimensional Culture System: A New Frontier in Cancer Research, Drug Discovery, and Stem Cell-Based Therapy. [PDF]

Biology (Basel)
Marconi GD, Mazzone A, Della Rocca Y, Trubiani O, Pizzicannella J, Diomede F.   +5 more
europepmc   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

The western transmission of traditional Chinese medicine: an investigation of the cultural elements of traditional Chinese medicine in biomedical systems of cross-Asia countries. [PDF]

Front Pharmacol
Kadier A, Ablimit M, Tursun H, Ablat N.
europepmc   +1 more source