Results 51 to 60 of about 46,631 (216)

Taraxerone inhibits M1 polarization and alleviates sepsis-induced acute lung injury by activating SIRT1

Chinese Medicine
Background Acute lung injury (ALI) is the most lethal disease associated with sepsis, and there is a lack of effective drug treatment. As the major cells of sepsis-induced ALI, macrophages polarize toward the proinflammatory M1 phenotype and secrete ...
Lang Deng, Weixi Xie, Miao Lin, Dayan Xiong, Lei Huang, Xiaohua Zhang, Rui Qian, Xiaoting Huang, Siyuan Tang, Wei Liu   +9 more
doaj   +1 more source

Flavonoid-rich fraction of Monodora tenuifolia Benth seeds improves antioxidant status in male Wistar rats with streptozotocin-induced Diabetes mellitus

Phytomedicine Plus
Background: Oxidative stress is a disruption in the balance between free radicals and the body's natural defenses. This study investigated the modulatory effect of a flavonoid-rich fraction of Monodora tenuifolia seed (FRFMTS) on oxidative stress and ...
Samuel Nzekwe, Adetoun Morakinyo, Monde Ntwasa, Sogolo Lebelo, Oluwafemi Oguntibeju, Oluokun Oyedapo, Ademola Ayeleso   +6 more
doaj   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

Fermentation alters the bioactive properties of kaempferol derived from horse gram extract

Phytomedicine Plus
Introduction: This study investigates the therapeutic potential of kaempferol, a metabolite from horse gram seeds, by comparing extracts from non-fermented and fermented sources.
Amber Rizwan, Husna Shaikh, Insha Latief, Waseem Ali, Adil Parvez, Kunal Malik, Sonam Grover, Humaira Farooqi   +7 more
doaj   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

Comparative analysis of phytochemical constituents in different parts of Aspilia africana: A potential medicinal plant for therapeutic applications

Phytomedicine Plus
Background: Among the diverse array of plants used in traditional medicine, Aspilia africana is highly valued due to its high efficacy against many ailments and its well-noted potential for wound healing.
Gerheart Winfred Ashong, Edward Ebow Kwaansa – Ansah, Mohammed Alhassan, Prince Nana Adofo, Jeremiah Adu Sarkodie, Boansi Adu Ababio   +5 more
doaj   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Adrenal hypertrophy in rats caused by 90-day force-feeding concomitant with the non-toxic effects of Antrodia cinnamomea

Phytomedicine Plus
Background: Antrodia cinnamomea (A. cinnamomea), a medicinal fungus native to Taiwan, has been used for decades by folk medicine practitioners to treat liver damage, cancer, and inflammation-related afflictions in Taiwan.
Chi-Tan Hu, Guan-Jhong Huang, Jayson John Taub, Ching-Feng Weng, David Yul, Huei Long   +5 more
doaj   +1 more source

Feeding, Fear, and Acceptance: Caregivers’ Experiences of Nutritional Support During Childhood Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques, Mariana dos Santos Murra, Welinton Hirai, Ana Laura Balduino do Nascimento, Karla Emilia de Sá Rodrigues, Wilson Elias de Oliveira Junior   +5 more
wiley   +1 more source

Protective effect of essential oil of Foeniculum vulgare Mill. against bleomycin-induced pulmonary fibrosis and oxidative stress in rat

Phytomedicine Plus
Background: Wild fennel (Foeniculum vulgare Mill.) is a very common plant used in traditional medicine to treat several diseases. In recent years, scientific research proved its biological properties.
Marwa Khammassi, Anouar Abidi, Naoures Ochi, Aida Ayadi, Yassine Mabrouk, Ismail Amri, Vincenzo De Feo, Hichem Sebai, Flavio Polito   +8 more
doaj   +1 more source