Results 121 to 130 of about 18,351,168 (336)

From ‘other’ to involved: User involvement in research: An emerging paradigm [PDF]

open access: yes, 2013
This article has been made available through the Brunel Open Access Publishing Fund. Copyright @ 2013 The Author(s). This is an Open Access article.
Barber R.   +25 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Turning to Animals Between Love and Law [PDF]

open access: yes, 2012
Publisher has granted permission for the published version of this article to be archived. Publisher's website: http://www.lwbooks.co.ukAs an alternative to Utilitarianism, animal ethics turned to the Continental philosophies of Levinas and Derrida that ...
PICK, A
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Discursive subjugation and the ways out: Narratives of othering among Czech Roma mothers

open access: yesRomani Studies
This paper introduces the analysis of biographical interviews focusing on the negotiation of the day-to-day child-raising by Czech Roma mothers. We demonstrate the narrative reflection of ethnic identity, as well as coping strategies and ways out of the ...
KATEŘINA SIDIROPULU-JANKŮ   +1 more
doaj   +1 more source

Allosemitism and cosmisation

open access: yesNordisk Judaistik, 2021
In this article, we explore the fruitfulness of seeing allosemitism as an aspect of cosmisation. We explore possible tropes such as creating order from chaos, embracing Christian identity and supersessionism, and legitimising the Bible’s truth claims ...
Jens Carlesson Magalhães   +1 more
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Representation of the Concept of Retirement in the Discourses of the Islamic Revolution in Iran (With Emphasis on the Law of Development Programs in the Country) [PDF]

open access: yesبهبود مدیریت, 2014
Although the issue of pensions is a major concern for most countries worldwide due to rising life expectancy and declining birth rates in recent decades, statistics and the status of pension funds in Iran show that Iranian society in recent years It will
Hamid Reza Fartokzadeh   +2 more
doaj  

From Rivalry to Mutual Trust: The Othering Process between Bolivia and Chile [PDF]

open access: yes
Bolivia and Chile live in a culture of rivalry as a consequence of the Nitrate War (1879-1883). In each country’s case, the construction of the other as a threat, a rival and/or inferior has shaped the discursive articulation of the bilateral ...
Leslie Wehner
core  

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