Results 151 to 160 of about 18,351,168 (336)
Introduction - veterinary science [PDF]
This introduction - co-written with Clare Palmer - sets up the following selection of open access essays in the 'living book': Veterinary Science: Animals, Humans and Health online at: http://www.livingbooksaboutlife.org/books ...
Fudge, Erica, Palmer, Clare
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Sustainability and the “urban peasant”: rethinking the cultural politics of food self-provisioning in the Czech Republic [PDF]
From the introduction: The third article, written by environmentalists Petr Jehlička and Joe Smith, overturns accounts of food self-provisioning in post-socialist Central and Eastern Europe that are rooted in myths of the “urban peasant”. After reviewing
Jehlička, Petr, Smith, Joe
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Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The Turkish Ordeal: Turkish Football Federation’s Stance Against the ‘Other’ [PDF]
Having an absolute monopoly on football in Turkey; Turkish Football Federation (‘TFF’) governs football through executive committee decisions and regulations put into force by it.
Abanazir, Cem
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