Results 91 to 100 of about 861,720 (342)

Enabling identity: The challenge of presenting the silenced voices of repressed groups in philosophic communities of inquiry [PDF]

open access: yes, 2016
This article seeks to contribute to the challenge of presenting the silenced voices of excluded groups in society by means of a philosophic community of inquiry composed primarily of children and young adults.
Kizel, Arie
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Poznawanie siebie i poznawanie innego. Wobec inności literatury

open access: yesPrzestrzenie Teorii, 2007
In my paper, I deal with the relationships between the present-day discourse in literature and literature itself: mainly in the aspect of the category of "otherness." Among many current understandings of that category, I analyse those for which ...
Anna Łebkowska
doaj   +1 more source

Am I lovin’ it? Tourists and the McDonald’s experience abroad [PDF]

open access: yes, 2009
Global organisations such as McDonald’s play a part in the tourist experience not only by offering food and drink, but also by providing other informal benefits such as clean toilets, air conditioning and increasingly wifi.
Johns, Nick, Osman, Hanaa
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Identidad, Alteridad y Extrañeza: entre la inclusión, la exclusión y la extrañeza radical [PDF]

open access: yes, 2011
This paper examines the relations between identity, otherness and alterity in the field of ethics and, especially, in that of political philosophy. For this, I refer to the work of three eminent thinkers: the Mexican philosopher Luis Villoro, and the ...
Leyva, Gustavo
core   +1 more source

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