Results 101 to 110 of about 31,801 (311)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Psychoanalysis and Education: the paradoxes of otherness
Educação & Realidade, 2013 This article approaches the concept of otherness in a correlation between Psychoanalysis and Education. As a condition for both disciplines a difference must be placed between the other as a peer; the inscription of the Other operating a particular ...
André Oliveira Costa +1 more
doaj
, 2003 The purpose of this paper is to provide a phenomenological examination of Otherness as it relates to the experience of being black in the America. The project begins with a summary of the Otherness theories of Emmanuel Levinas, Jean-Paul Sartre, and ...
I\u27Anson, Chioke A. M
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
PROJECTIONS OF OTHERNESS IN INDIAN DIASPORIC WRITING [PDF]
, 2017 The given paper focuses on the concept of otherness and its representation in the works of contemporary Indian-origin UK-based writers Amit Chaudhuri, Neel Mukherjee and Mirza Waheed.
Alina Nidagundi
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Studia Universitatis Babeş-Bolyai. MusicaThe present article aims to reveal the methods used by 19th century French composers when representing Otherness. The concept of Otherness (alterity) was often associated with Orientalism, the representation of foreign cultures offering Western artists ...
Mădălina Dana RUCSANDA +1 more
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Consciousness, Otherness and Hospitality
, 2019 This is an edited excerpt from the 2019 ASAL Patron’s Lecture, Detours and Divagations: Consciousness, Otherness and Hospitality, delivered on 14 March 2019 at the Io Myers Studio, University of New South Wales.This is an edited excerpt from the 2019 ...
Castro, B.A.
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