Results 121 to 130 of about 163,047 (311)
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Continuum Belief, Categorical Belief, and Depression Stigma: Correlational Evidence and Outcomes of an Online Intervention [PDF]
Continuum belief interventions that erode boundaries between “normal” individuals and individuals with psychiatric problems may help to reduce psychiatric stigma, but a number of questions persist.
Thibodeau, Ryan
core +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Constructing the other: managerial rhetorics of diversity. [PDF]
In this article, we examine how HR managers rhetorically construct diversity as discourses of Otherness. Our analysis relies on argument schemes developed by the classical rhetoric tradition.
Janssens, Maddy, Zanoni, Patrizia
core
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Critical dialogues: slow readings of English literary texts [PDF]
The reader will find gathered together in this volume a selection of articles and essays that have been separately published over the past three decades as a result of my teaching practice and research activity. In chronological terms, they span a period
Correia, Maria Helena de Paiva, 1944- +1 more
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Visions of China: Avant-Orientalism, Art Rock, and Conflicted Otherness
The essay reexamines the countercultural positionality of art rock musical works by considering the often-dismissed correlations between Western rock and the Oriental. Introducing the concept of Orientalism to Lawrence Grossberg’s five- hypothesis
Gabriele
doaj
[Review of] Jennifer S.H. Brown and Robert Brightman. The Orders of the Dreamed :George Nelson on Cree and Northern Ojibwa Religion and Myth, 1823 [PDF]
This text addresses the complex challenge of comprehending religious otherness. Brown and Brightman present a previously unpublished 1823 letter journal of fur trader George Nelson in which he reflects on his struggle to understand the Cree and Ojibwa ...
Morrison, Kenneth M.
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source

