Results 81 to 90 of about 861,720 (342)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

A másság iránti tolerancia és a hatalom viszonya

open access: yesSymbolon, 2020
The Relationship of Power and Tolerance Concerning Otherness If we try to visualize the standard accepted by our self-image and environment, is the other image differ-ent from ours, the otherness abnormal? When appearance, attitude different from ours
Anna Kós
doaj  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Other territories / other exchanges: Other territories / other exchanges

open access: yes, 2020
This article reviews the community relations at plaza de hierbas del Samper Mendoza, in Bogotá. These dynamics of cooperation, dialogue and negotiation of space produce an Other Territory (territorios otros). Part of the understanding of this is given through the review of primary sources that indicated the origin of farmers markets in Bogotá, to ...
Duque Jamaica, Camila   +1 more
openaire   +2 more sources

Introduction: ‘Crossing into Otherness’

open access: yesÉtudes Britanniques Contemporaines, 2015
In this opening section of Études britanniques contemporaines 48, we try to explore how the very experience of displacement or crossing entails a process of alteration through which we are both estranged and reinvented.
Catherine Bernard
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Sí mismo para otro. Un debate sobre ética e identidad en Emmanuel Levinas y Paul Ricoeur

open access: yesFranciscanum, 2013
Through the notion of narrative identity, Paul Ricoeur tries to show how the relationship between identity and otherness implies a dialectic between the own and the alien, present in all understanding.
Pedro Enrique García Ruiz
doaj  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Learning from Bad Teachers: Leibniz as a Propaedeutic for Chinese Philosophy [PDF]

open access: yes, 2016
One of the challenges facing instructors of Chinese philosophy courses at many Western universities is the fact that students can often bring orientalizing assumptions and expectations to their encounters with primary sources.
DeLapp, Kevin
core   +1 more source

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