Results 11 to 20 of about 56,531 (219)

Identification of Differential Metabolites in Chronic Suppurative Otitis Media With Non-Targeted and Targeted Metabolomics Approach. [PDF]

Smart Med
Untargeted metabolomics is used to analyze tissue samples from chronic suppurative otitis media patients with or without cholesteatoma and identify metabolic differences across groups stratified by CT scores. Targeted metabolomic validation in an independent cohort verified five candidate metabolites. ABSTRACT Chronic suppurative otitis media (CSOM) is
Hu L, Zhu Y, Wu C, Liu X, Wang Q, Huang Y, Liu H, Chen X, Wu W, Jiang H.   +9 more
europepmc   +2 more sources

Surgical and Conservative Management in Otitic Barotrauma: A Retrospective Cohort Study. [PDF]

OTO Open
Abstract Objective Analyze the relationship between surgical and non‐surgical interventions for otitic barotrauma (OB), and identify underlying medical diagnosis, recurrence rates, and treatment outcomes. Study Design Retrospective cohort analysis. Setting TriNetX US collaborative network.
Khan FI, Vazquez SG, Vannier AGL, Dongre R, Ahmed OG, Imbery TE, Vrabec JT.   +6 more
europepmc   +2 more sources

Improving Tympanoplasty: Transverse External Auditory Canal Flap Advancement. [PDF]

Laryngoscope Investig Otolaryngol
We conducted this study to investigate the clinical outcomes of a new self‐created technique for improving tympanoplasty. This technique, called the external auditory canal flap advancement method, aims to treat large tympanic membrane perforations, particularly those without residual edges at the anterior margin.
Gao X, Qi W, Yuan F, Liu C, Li H, Dong Y, Cao X, Li C, Xia M, Xie F.   +9 more
europepmc   +2 more sources

Fluoroscopic guidance for bulla identification during ventral bulla osteotomy in eight French bulldogs. [PDF]

Vet Rec Open
Abstract Objective To describe the technique and outcome of fluoroscopy to guide bulla identification in French bulldogs during ventral bulla osteotomy. Materials and methods Medical records of eight French bulldogs with otitis media that underwent a fluoroscopic‐guided ventral bulla osteotomy between January 2020 and June 2023 were reviewed ...
Lu HY, Biskup JJ, Mehrkens LR, Reynolds D.   +3 more
europepmc   +2 more sources

Systematic Review and Meta-Analysis of Audiometric Parameters for Assistive Hearing Technology for Adults and Children With Tympanic Membrane Perforation. [PDF]

Clin Otolaryngol
ABSTRACT Introduction Tympanic membrane perforation can cause hearing impairment with detrimental effects on communication and quality of life, and is a problem affecting an estimated 250 million people. To date, there is little analysis to inform public policy on options for assistive hearing technology rehabilitation in this group.
Hampton T, Sanderson A, Mortimer K, Bhutta M.   +3 more
europepmc   +2 more sources

Antibiotics for sore throat [PDF]

, 2013
Background: Sore throat is a common reason for people to present for medical care. Although it remits spontaneously, primary care doctors commonly prescribe antibiotics for it.
Del Mar, Chris B., Glasziou, Paul P., Spinks, Anneliese   +2 more
core   +1 more source

Bacteriological Profile of Chronic Suppurative Otitis Media and Antibiotic Susceptibility in a Tertiary Care Hospital in Shanghai, China

Ear, nose, & throat journal, 2020
Objective: Chronic suppurative otitis media (CSOM) is mostly caused by bacterial infection of the middle ear and antibiotics are generally used empirically, which may lead to the emergence of resistant bacterial strains.
Jianghong Xu, Q. Du, Y. Shu, Jian Ji, Chunfu Dai   +4 more
semanticscholar   +1 more source

Ototopical drops containing a novel antibacterial synthetic peptide: Safety and efficacy in adults with chronic suppurative otitis media

PLoS ONE, 2020
Objective Chronic suppurative otitis media (CSOM) is a chronic infectious disease with worldwide prevalence that causes hearing loss and decreased quality of life.
Nanno F A W Peek, M. J. Nell, R. Brand, Thekla Jansen-Werkhoven, E. V. van Hoogdalem, R. Verrijk, M. Vonk, A. Wafelman, A. Valentijn, J. Frijns, P. Hiemstra, J. Drijfhout, P. Nibbering, J. J. Grote   +13 more
semanticscholar   +1 more source

Ear, nose and throat injuries at Bugando Medical Centre in northwestern Tanzania: a five-year prospective review of 456 cases. [PDF]

, 2013
Injuries to the ear, nose and throat (ENT) regions are not uncommon in clinical practice and constitute a significant cause of morbidity and mortality in our setting. There is dearth of literature on this subject in our environment.
BC Okoye, BC Okoye, Bugando Medical Centre (BMC), D Trunkey Donald, EG Kang, FT Orji, I Matilda, I Matilda, I Singh, Japhet M Gilyoma, JM Gilyoma, LC Synders, M Liberman, OA Sogebi, Phillipo L Chalya, RK Arif, RK Arif, RR Figueriedo, S Endican, SK Aremu, SM Mutooro   +20 more
core   +2 more sources

A novel mouse model of chronic suppurative otitis media and its use in preclinical antibiotic evaluation

Science Advances, 2020
A novel mouse model of chronic ear infections is used to investigate antibiotic failure in humans. Chronic suppurative otitis media (CSOM) is a neglected pediatric disease affecting 330 million worldwide for which no new drugs have been introduced for ...
K. Khomtchouk, A. Kouhi, A. Xia, L. Bekale, S. Massa, Jolien M. Sweere, D. Pletzer, R. Hancock, P. Bollyky, P. L. Santa Maria   +9 more
semanticscholar   +1 more source