Results 61 to 70 of about 13,557 (247)
Dual AAV gene therapy achieves recovery of hearing and auditory processing in a DFNB16 mouse model
Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.DFNB16 is among the most prevalent forms of congenital deafness, caused by mutations in the Stereocilin gene. Although no treatment currently exists, gene therapy represents a promising curative approach. Here, we demonstrate that AAV‐mediated gene delivery in a DFNB16 mouse model restored both peripheral hearing and central auditory processing ...
Sepideh Iranfar +12 more
wiley +1 more source
HNO, 1993 Spontaneous sound signals emitted from the inner ear were first recorded by Kumpf and Hoke in 1970. Kemp reported phenomena of sounds which were emitted by the ear responding to acoustic stimulation. These "otoacoustic emissions" are supposed to be generated in the outer hair cells.
openaire +4 more sources
Empirical and biophysical estimations of human cochlea’s psychophysical tuning curve sharpness
AIP Advances, 2016 Despite the advances in cochlear research, the estimation of auditory nerve fiber frequency tuning of human cochlea is mostly based on psychophysical measurements.
Wei Xuan Chan +2 more
doaj +1 more source
Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.In this Chinese family with hereditary deafness, we identified a novel DIAPH3 point variant (NM_001042517.2:c.1472A>G). This variant manifests as late‐onset progressive sensorineural hearing loss, with congruent pure‐tone audiometry (PTA) and auditory brainstem response (ABR) thresholds.
Lingling Zeng +8 more
wiley +1 more source
Archives of Acoustics, 2018 The main purpose of this research was to determine the influence of a therapeutic dose of an opioid drug (methadone) on selected auditory functions in patients addicted to opioids (recognition ICD-10; F11) and undergoing substitution therapy.
Emilia TARNOWSKA +3 more
doaj +1 more source
Aging Cell, Volume 25, Issue 1, January 2026.Chronic low‐concentration lead exposure accelerates the development of ARHL. Lead exposure mediates damage to cochlear sensory cells via the mitochondrial protease LONP1, leading to irreversible hearing loss. ABSTRACT Heavy metal ion exposure has become a global public health concern.
Xue Bai +10 more
wiley +1 more source
Development of learning objectives for neurology in a veterinary curriculum: Part II: Postgraduates [PDF]
, 2015 Background: Specialization in veterinary medicine in Europe is organized through the Colleges of the European Board of Veterinary Specialization. To inform updating of the curriculum for residents of the European College of Veterinary Neurology (ECVN ...
Anderson, T J +13 more
core +6 more sources
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2010 Introduction: Otoacoustic emissions are low density sounds produced from intact cochlea measureable in the presence of an intact conduction structure.
MH Baradaranfar +6 more
doaj
Evaluation and Importance of Our Newborn Hearing Screening Results
Haseki Tıp Bülteni, 2017 Amaç: Bu çalışmada, Konya Beyhekim Devlet Hastanesi’nde doğmuş tüm yenidoğanların işitme tarama sonuçlarını ve işitme kaybı olan bebeklerin risk faktörlerini güncel literatür eşliğinde paylaşmayı amaçladık.
Alaaddin Yorulmaz +3 more
doaj +1 more source
Unraveling the Role of WDR91: Case Report of a Previously Unrecognized Clinical Entity
Clinical Genetics, Volume 109, Issue 1, Page 176-180, January 2026.A novel case is herein described to expand the genetic and clinical spectrum of WDR91 and characterize a previously unrecognized autosomal recessive neurodevelopmental disorder. WDR91 deficiency results in neuronal loss, cortical thinning, and impaired brain development.
Nikolaos M. Marinakis +14 more
wiley +1 more source