Results 41 to 50 of about 1,164,986 (198)

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

open access: yesAdvanced Science, Volume 13, Issue 20, 9 April 2026.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling   +17 more
wiley   +1 more source

Comparative Prognostic Analysis of Sudden Sensorineural Hearing Loss With Vertigo in Pediatric and Adult Patients

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 2, April 2026.
ABSTRACT Objective To compare the association of vertigo with rates of frequency‐specific hearing recovery in pediatric and adult patients with unilateral idiopathic sudden sensorineural hearing loss (SSNHL). Methods A total of 80 pediatric and 444 adult patients hospitalized with SSNHL were included in this study.
Changshuo Shan   +8 more
wiley   +1 more source

Influence of Spontaneous Otoacoustic Emission (SOAE) on Transiently Evoked Otoacoustic Emission (TEOAE).

open access: yesNippon Jibiinkoka Gakkai Kaiho, 2000
The literature has reports on the influence of spontaneous otoacoustic emission (SOAE) on transiently evoked otoacoustic emission (TEOAE), but most do not take factors such as age, gender, and hearing level into consideration. We focused on these conditions. Subjects were 78 women with normal hearing aged 19 to 24 years (mean = 21.4). All had pure tone
Kuroda, Tsutomu   +7 more
openaire   +3 more sources

Study on suppression of otoacoustic emissions: lateral domain Estudo da supressão da amplitude das emissões otoacústicas: dominância lateral

open access: yesBrazilian Journal of Otorhinolaryngology, 2011
A pon stimulation by contralateral, ipsilateral or bilateral noise, the medial olivocochlear efferent tract changes the amplitude of otoacoustic emissions relative to the tested ear, reducing or removing it; this resulted in a reduction/suppression ...
Jerusa Roberta Massola de Oliveira   +2 more
doaj   +1 more source

Brimonidine Therapy for Protection From Noise‐Induced Hearing Loss

open access: yesAging Cell, Volume 25, Issue 4, April 2026.
In this study, we demonstrate that brimonidine protects against noise‐induced hearing loss in young mice by suppressing glutamate synthesis and vesicle transport, thereby reducing excitotoxicity and preserving synaptic integrity. Such early intervention may prevent age‐related hearing loss, highlighting brimonidine's potential as a therapeutic agent ...
Jing Cai   +10 more
wiley   +1 more source

An Active Oscillator Model Describes the Statistics of Spontaneous Otoacoustic Emissions [PDF]

open access: yes, 2014
Even in the absence of external stimulation, the cochleas of most humans emit very faint sounds below the threshold of hearing, sounds that are known as spontaneous otoacoustic emissions.
Jülicher, Frank   +5 more
core   +1 more source

Auditory Neuropathy: Challenges and Significant Progress in Diagnosis and Treatment

open access: yesAdvanced Therapeutics, Volume 9, Issue 3, March 2026.
Auditory neuropathy is a complex disorder that causes sensorineural hearing impairment in patients. Recently, breakthrough progress has been made in the gene therapy of auditory neuropathy. This review focuses on auditory neuropathy, covering its pathophysiology, etiology, epidemiology, clinical manifestations, diagnostic techniques, treatment ...
Wen Xie   +11 more
wiley   +1 more source

Alterações auditivas em crianças expostas à toxoplasmose durante a gestação

open access: yesRevista CEFAC
RESUMO Objetivo: verificar a ocorrência e o tipo mais frequente de alteração auditiva em crianças expostas a toxoplasmose durante a gestação. Métodos: estudo retrospectivo longitudinal realizado em instituição pública de saúde de São Paulo.
Carlos Alberto Leite Filho   +6 more
doaj   +1 more source

Clinical and Genetic Characteristics of Free Sialic Acid Storage Disorder

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Free sialic acid storage disorder (FSASD) is a lysosomal storage disorder that results from biallelic pathogenic variants in the SLC17A5 gene. This gene codes for sialin, a 12‐transmembrane domain protein that exports the charged sugar N‐acetylneuraminic acid (Neu5Ac; sialic acid) out of the lysosome.
Zoe Wolfenson   +18 more
wiley   +1 more source

Modeling the characteristics of spontaneous otoacoustic emissions in lizards

open access: yesHearing Research, 2020
Lizard auditory papillae have proven to be an attractive object for modelling the production of spontaneous otoacoustic emissions (SOAE). Here we use an established model (Vilfan and Duke, 2008) and extend it by exploring the effect of varying the number of oscillating elements, the strength of the parameters that describe the coupling between ...
Wit, Hero P.   +2 more
openaire   +2 more sources

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