Results 31 to 40 of about 10,617 (213)
The State of High‐Resolution Imaging of the Human Inner Ear: A Look Into the Black Box
Advanced Science, EarlyView.High‐resolution imaging of the cochlea is challenged by numerous unique aspects of this organ, where sensorineural cells, crucial for hearing, are too small for conventional modalities like magnetic resonance imaging and computed tomography. This article reviews current imaging techniques, emerging technologies, and innovations aimed at improving ...
Shelley Batts +3 more
wiley +1 more source
Visualization of the Spiral Ganglion Neuron in Vivo Using a Novel 177Lu Nuclear Molecule Label
Advanced Science, EarlyView.The study developed and validated a radionuclide‐labeled anti‐VGLUT1 antibody probe for the first nuclear imaging of cochlear spiral ganglion neurons (SGNs) in vivo. This approach may provide aid in screening candidates suitable for CI surgery by quantifying the number of surviving SGNs, and predicting the potential for postoperative hearing ...
Chenyang Kong +11 more
wiley +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The MT‐ATP6 gene m.8993T>G pathogenic variant has been associated with Leigh syndrome, especially in patients exhibiting a high degree of heteroplasmy. Although patients may present with a wide phenotypic spectrum, characteristic findings include bilateral, symmetric hyperintensities in the basal ganglia and brainstem on brain MRI ...
Ramya Treitel +2 more
wiley +1 more source
An Evaluation of Otoacoustic Emissions as a Biometric [PDF]
IEEE Transactions on Information Forensics and Security, 2013 This paper presents a comprehensive overview of an investigation into the use of otoacoustic emissions (OAE) as an identity verification biometric. OAE could be important as a biometric identifier in applications where users wear headsets since it is discrete and difficult to spoof.
Grabham, N.J. +6 more
openaire +3 more sources
New insights into applications of base editor in hereditary disorders
Interdisciplinary Medicine, EarlyView.Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai +8 more
wiley +1 more source
Patterns of Teprotumumab‐Induced Hearing Dysfunction: A Systematic Review
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective Hearing loss has been reported after administration of the monoclonal antibody teprotumumab. The purpose of this study was to review available evidence regarding the patterns of teprotumumab‐related ototoxicity. Data Sources PubMed, EMBASE, and Cochrane Library.
Kevin Wong +8 more
wiley +1 more source
Chinese Clinical Practice Guidelines for Auditory Neuropathy (gCAN)
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Auditory neuropathy (AN) is an auditory disorder that affects the function of the auditory pathway. An increasing number of AN cases have been identified with the revelation of the underlying mechanisms, the advancements of diagnostic and detecting techniques.
Chinese Multi‐Center Research Collaborative Group on Clinical Diagnosis and Intervention of Auditory Neuropathy; Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery; Society of Otorhinolaryngology Head and Neck Surgery +43 more
wiley +1 more source
Unraveling the Role of WDR91: Case Report of a Previously Unrecognized Clinical Entity
Clinical Genetics, EarlyView.A novel case is herein described to expand the genetic and clinical spectrum of WDR91 and characterize a previously unrecognized autosomal recessive neurodevelopmental disorder. WDR91 deficiency results in neuronal loss, cortical thinning, and impaired brain development.
Nikolaos M. Marinakis +14 more
wiley +1 more source
Revista CEFAC, 2009 OBJETIVO: comparar o nível de resposta e o tempo de latência das emissões otoacústicas sem e com apresentação de ruído contralateral. MÉTODOS: foram avaliados 30 indivíduos, com idade entre 18 e 30 anos, sem queixas auditivas e com presença de emissões ...
Vanessa Nogueira Leme +1 more
doaj
Evaluation of Hearing and Outer Hair Cell Function of Cochlea in Patients With Psoriatic Arthritis [PDF]
Clinical and Experimental Otorhinolaryngology, 2015 ObjectivesThe aim of this study was to investigate hearing and outer cells function in patients with psoriatic arthritis. Our investigation was a prospective case control study.MethodsA total of 31 psoriatic arthritis patients (62 ears) and 31 healthy ...
Mehmet Akdag +5 more
doaj +1 more source