Results 41 to 50 of about 1,814,014 (255)

DISTORTION PRODUCT OTOACOUSTIC EMISSIONS IN NORMAL - HEARING WORKERS EXPOSED TO OCCUPATIONAL NOISE [PDF]

Revista Gestão & Saúde, 2013
Introduction-The otoacoustic emissions test has been highlighted by thepossibility of detecting early cochlear changes resulting from exposureto noise, not identifiedby audiometry.Objective: To evaluate the distortion product otoacoustic emissions ...
Marlene Escher Boger, André Luiz Lopes Sampaio, Carlos Augusto da Costa Pires de Oliveira   +2 more
doaj  

Otoacoustic emission measurements: a test–retest reliability study

The Egyptian Journal of Otolaryngology, 2023
Objectives Otoacoustic emissions (OAEs) are an important part of the audiological test battery and have many clinical uses. This study aims to determine the amplitude changes in the test–retest condition of distortion product otoacoustic emissions ...
Ayşenur Aykul Yağcıoğlu, Burak Öztürk   +1 more
doaj   +1 more source

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

Advanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang, Yuehui Xi, Qiaojun Fang, Sai Shi, Fei Wang, Fuyu Xian, Zhongyang Zhang, Yuxin Yang, Xishuo Jin, Xiaomin Wang, Chen Cao, Hailin Zhang, Nikita Gamper, Zhigang Xu, Haitao Shen, Ping Lv   +15 more
wiley   +1 more source

Visualization of the Spiral Ganglion Neuron in Vivo Using a Novel 177Lu Nuclear Molecule Label

Advanced Science, EarlyView.
The study developed and validated a radionuclide‐labeled anti‐VGLUT1 antibody probe for the first nuclear imaging of cochlear spiral ganglion neurons (SGNs) in vivo. This approach may provide aid in screening candidates suitable for CI surgery by quantifying the number of surviving SGNs, and predicting the potential for postoperative hearing ...
Chenyang Kong, Xiaohui Wang, Jintao Yu, Li Wen, Chengwen Zheng, Ge Yin, Kai Xu, Weiwei He, Hao Wang, Xiaoli Lan, Dawei Jiang, Yu Sun   +11 more
wiley   +1 more source

Case Report: Unusual Neurological Features of Leigh Syndrome due to m.8993T>G Pathogenic Variant in the MT‐ATP6 Gene

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The MT‐ATP6 gene m.8993T>G pathogenic variant has been associated with Leigh syndrome, especially in patients exhibiting a high degree of heteroplasmy. Although patients may present with a wide phenotypic spectrum, characteristic findings include bilateral, symmetric hyperintensities in the basal ganglia and brainstem on brain MRI ...
Ramya Treitel, Julie McLaughlin, Marta Frigeni   +2 more
wiley   +1 more source

Ipsilateral cochlear implantation in cases with vestibular schwannoma

Eye &ENT Research, EarlyView.
Abstract Background Vestibular schwannomas (VS) are the most common tumors in the cerebellopontine angle, which can lead to hearing loss, particularly following tumor resection. For patients with bilateral VS associated with neurofibromatosis type 2 (NF2), hearing loss significantly undermines their quality of life.
Qian Wan, Ruotong Wang, Yaqin Wu, Dongzhen Yu, Haibo Shi, Jingjing Wang, Pengjun Wang, Zhengnong Chen   +7 more
wiley   +1 more source

New insights into applications of base editor in hereditary disorders

Interdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai, Linhui Zhang, Liqing Li, Yue Liu, Canbin Lv, Yan Shi, Jianyuan Zhao, Dingwei Ye, Yuanyuan Qu   +8 more
wiley   +1 more source

Patterns of Teprotumumab‐Induced Hearing Dysfunction: A Systematic Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Hearing loss has been reported after administration of the monoclonal antibody teprotumumab. The purpose of this study was to review available evidence regarding the patterns of teprotumumab‐related ototoxicity. Data Sources PubMed, EMBASE, and Cochrane Library.
Kevin Wong, Priya Arya, Yansy Salmeron, Douglas C. Bigelow, Michael J. Ruckenstein, Shubhasree Banerjee, Madhura Tamhankar, Jason A. Brant, Tiffany P. Hwa   +8 more
wiley   +1 more source

Measuring stimulus-frequency otoacoustic emissions using swept tones.

Journal of the Acoustical Society of America, 2013
Although stimulus-frequency otoacoustic emissions (SFOAEs) offer compelling advantages as noninvasive probes of cochlear function, they remain underutilized compared to other evoked emission types, such as distortion-products (DPOAEs), whose measurement ...
Radha Kalluri, C. Shera
semanticscholar   +1 more source

Evaluation of Hearing and Outer Hair Cell Function of Cochlea in Patients With Psoriatic Arthritis [PDF]

Clinical and Experimental Otorhinolaryngology, 2015
ObjectivesThe aim of this study was to investigate hearing and outer cells function in patients with psoriatic arthritis. Our investigation was a prospective case control study.MethodsA total of 31 psoriatic arthritis patients (62 ears) and 31 healthy ...
Mehmet Akdag, Derya Uçmak, Fazıl Emre Özkurt, Mehtap Bozkurt, Zeynep Meltem Akkurt, İsmail Topçu   +5 more
doaj   +1 more source