Results 51 to 60 of about 1,887,030 (250)

Ototoxicity and otoprotection in the inner ear of guinea pigs using gentamicin and amikacin: ultrastructural and functional aspects

Brazilian Journal of Otorhinolaryngology, 2008
Summary: Ototoxicity is still a challenge to medicine. The discovery of self-protecting endogenous mechanisms of the outer hair cells associated with their functional and ultra-structural assessment methods has opened new horizons in the understanding ...
Thomaz José Marra de Aquino, José Antônio Apparecido de Oliveira, Maria Rossato   +2 more
doaj   +1 more source

Brainstem auditory evoked responses in an equine patient population: part I--adult horses. [PDF]

, 2014
BackgroundBrainstem auditory evoked response has been an underused diagnostic modality in horses as evidenced by few reports on the subject.Hypothesis/objectivesTo describe BAER findings, common clinical signs, and causes of hearing loss in adult horses ...
Aleman, M, Holliday, TA, Nieto, JE, Williams, DC   +3 more
core   +1 more source

Electrocochleographic Changes Predict an Early Sign of Cochlear Degeneration

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives The purpose of this study is to identify the earliest appearing auditory electrophysiological indicators that change with age progression in young adults with normal hearing, and to analyze the frequency distribution patterns of these markers in the cochlear.
Min‐Fei Qian, Hao Chen, Qi‐Xuan Wang, Ya‐Qi Zhou, Xiao‐Lu Chen, Zhi‐Wu Huang, Ji‐Ping Li   +6 more
wiley   +1 more source

Sensory hyperacusis as a predictor of anxiety in adolescence

Journal of Child Psychology and Psychiatry, EarlyView.
Background An increasing number of children report anxiety in early to mid‐adolescence. Early identification of risk during the transition from primary to secondary schools (age 11) could enhance family‐ or school‐based interventions. While known predictors of adolescent anxiety provide some insight, there is a need to identify and understand ...
Foteini Tseliou, Stephan Collishaw, Alice Price, Petroc Sumner   +3 more
wiley   +1 more source

Determination and evaluation of clinically efficient stopping criteria for the multiple auditory steady-state response technique [PDF]

, 2009
Background: Although the auditory steady-state response (ASSR) technique utilizes objective statistical detection algorithms to estimate behavioural hearing thresholds, the audiologist still has to decide when to terminate ASSR recordings introducing ...
D'Haenens, Wendy, Dhooge, Ingeborg, Vinck, Bart   +2 more
core   +1 more source

Type II spiral ganglion afferent neurons drive medial olivocochlear reflex suppression of the cochlear amplifier. [PDF]

, 2015
The dynamic adjustment of hearing sensitivity and frequency selectivity is mediated by the medial olivocochlear efferent reflex, which suppresses the gain of the 'cochlear amplifier' in each ear.
Cederholm, Jennie ME, Froud, Kristina E, Housley, Gary D, Julien, Jean-Pierre, Klugmann, Matthias, Ryan, Allen F, Sandow, Shaun L, Wong, Ann Chi Yan   +7 more
core   +2 more sources

Clinical Diagnostics After Failed Hearing Screening in People With Intellectual Disabilities Do Not Often Take Place

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Individuals with intellectual disabilities are at higher risk of undiagnosed or inadequately treated hearing loss. This situation requires easily accessible hearing screening, diagnostics and intervention programmes in the living environment, i.e., in nurseries, schools, workplaces and homes.
Anna Wiegand, Philipp Mathmann, Susanne Wasmuth, Lukas Prein, Ross Parfitt, Martin Scharpenberg, Vincent Jankovic, Katharina Schwarze, Anja Neumann, Karolin Schäfer, Christian Speckemeier, Sven Baessler, Sarah Schlierenkamp, Sandra Diekmann, Nicole Stuhrmann, Ruth Lang‐Roth, Muhittin Demir, Werner Brannath, Awa Naghipour, Susanna Marie Zielonkowski, Anna Sophia Schwalen, Corinna Gietmann, Katrin Neumann   +22 more
wiley   +1 more source

Altered Auditory Maturation in Fragile X Syndrome and Its Involvement in Audiogenic Seizure Susceptibility

Autism Research, Volume 19, Issue 1, January 2026.
ABSTRACT Auditory hypersensitivity is a prominent symptom in Fragile X syndrome (FXS), the most prevalent monogenic cause of autism and intellectual disability. FXS arises through the loss of the protein encoded by the FMR1 (Fragile X Messenger Ribonucleoprotein 1) gene, FMRP, required for normal neural circuit excitability.
Dorit Möhrle, Demi Ma, Wenyue Xue, Jun Yan, Ning Cheng   +4 more
wiley   +1 more source

Dual AAV gene therapy achieves recovery of hearing and auditory processing in a DFNB16 mouse model

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
DFNB16 is among the most prevalent forms of congenital deafness, caused by mutations in the Stereocilin gene. Although no treatment currently exists, gene therapy represents a promising curative approach. Here, we demonstrate that AAV‐mediated gene delivery in a DFNB16 mouse model restored both peripheral hearing and central auditory processing ...
Sepideh Iranfar, Sophie Bagur, Chloé Felgerolle, Maxence Cornille, Najate Benamer, Hélène Le Ribeuz, Marie Giorgi, Sara Jamali, Amel Saoudi, Marie‐José Lecomte, Vincent Michel, Brice Bathellier, Saaid Safieddine   +12 more
wiley   +1 more source

Evaluation of Hearing and Outer Hair Cell Function of Cochlea in Patients With Psoriatic Arthritis [PDF]

Clinical and Experimental Otorhinolaryngology, 2015
ObjectivesThe aim of this study was to investigate hearing and outer cells function in patients with psoriatic arthritis. Our investigation was a prospective case control study.MethodsA total of 31 psoriatic arthritis patients (62 ears) and 31 healthy ...
Mehmet Akdag, Derya Uçmak, Fazıl Emre Özkurt, Mehtap Bozkurt, Zeynep Meltem Akkurt, İsmail Topçu   +5 more
doaj   +1 more source