Vestibular Drop Attacks and Meniere's Disease as Results of Otolithic Membrane Damage-A Numerical Model. [PDF]
AbstractMeniere’s disease (MD) is a condition of the inner ear with symptoms affecting both vestibular and hearing functions. Some patients with MD experience vestibular drop attacks (VDAs), which are violent falls caused by spurious vestibular signals from the utricle and/or saccule.
Senofsky N, Faber J, Bozovic D.
europepmc +10 more sources
Otolithic membrane damage in patients with endolymphatic hydrops and drop attacks. [PDF]
1. Evaluate the otolithic membrane in patients with endolymphatic hydrops (EH) and vestibular drop attacks (VDA) undergoing ablative labyrinthectomy. 2. Correlate intraoperative findings to archival temporal bone specimens of patients with EH.Retrospective case review.Tertiary referral center. SPECIMEN SOURCE: 1. Patients undergoing labyrinthectomy for
Calzada AP+3 more
europepmc +7 more sources
Transversal otolithic membrane deflections evoked by the linear accelerations [PDF]
Considered is the model of the transversal utricle membrane deflections evoked by the linear accelerations. The basic idea underlying this consideration is that the linear accelerations can cause both longitudinal and transversal deformations when acting along the membrane in the buckling way.
V. Goussev
semanticscholar +6 more sources
Motion of the otolithic membrane in the bullfrog sacculus [PDF]
Accessory structures that overlie the sensory epithelia of the various inner ear organs play an important role in the transduction of mechanical perturbations by the underlying hair cells. It imposes a load (mass, offset in position) on individual hair bundles and is the medium that mechanically couples multiple hair bundles.
Sebastiaan W. F. Meenderink+1 more
semanticscholar +4 more sources
An Electron Microscopic Study of the Otolithic Membrane
Morphological studies were made of the otolithic membrane in its normal and pathological states in guinea pig, mice and squirrel monkey using scanning and transmission electron microscopes.The otolithic membrane normally consists of three layers; the first layer, situated nearest the endolymph, is an otoconial layer wherein otoconia of calcite form of ...
Akiko Morimoto, Yoshiaki Nakai
semanticscholar +4 more sources
Electron Probe Microanalysis of the Otolithic Membrane. A Methodological and Quantitative Study [PDF]
The effect of tissue preparation on calcium and potassium weight percents in the otoconial layer in the utricle and saccule was studied in four groups of OF1 mice with electron probe X-ray microanalysis.
Campos, A.+3 more
core +5 more sources
Normal Serum Levels of Otolin-1 in Patients with Meniere Disease in Remission [PDF]
Introduction Degenerative changes in the otolithic organs have been theorized to be caused by the mechanical obstruction to endolymphatic flow, possibly resulting in endolymphatic hydrops (ELH).
Anup Singh+5 more
doaj +2 more sources
A New Perspective to Interpret How the Vestibular Efferent System Correlates the Complexity of Routine Balance Maintenance with Management of Emergency Fall Prevention Strategies [PDF]
Bipedalism is unique among mammals. Until modern times, a fall and resulting leg fracture could be fatal. Balance maintenance after a destabilizing event requires instantaneous decision making.
Neil S. Longridge, Arthur I. Mallinson
doaj +2 more sources
Coupling and elastic loading affect the active response by the inner ear hair cell bundles. [PDF]
Active hair bundle motility has been proposed to underlie the amplification mechanism in the auditory endorgans of non-mammals and in the vestibular systems of all vertebrates, and to constitute a crucial component of cochlear amplification in mammals ...
Clark Elliott Strimbu+2 more
doaj +5 more sources
Presence of chondroitin sulphate and requirement for heparan sulphate biosynthesis in the developing zebrafish inner ear [PDF]
Epithelial morphogenesis to form the semicircular canal ducts of the zebrafish inner ear depends on the production of the large glycosaminoglycan hyaluronan, which is thought to contribute to the driving force that pushes projections of epithelium into ...
Ana A. Jones+3 more
doaj +2 more sources