Results 31 to 40 of about 1,087,515 (186)

Factors influencing the solubilization of membrane proteins from Escherichia coli membranes by styrene–maleic acid copolymers [PDF]

, 2020
Styrene–maleic acid (SMA) copolymers are a promising alternative to detergents for the solubilization of membrane proteins. Here we employ Escherichia coli membranes containing KcsA as a model protein to investigate the influence of different ...
Dörr, Jonas M., Sub Membrane Biochemistry & Biophysics, Membrane Biochemistry and Biophysics, Koorengevel, Martijn C., Jahn, Helene, Killian, J. Antoinette, Antoniciello, Federico, Kopf, Adrian H.   +7 more
core   +1 more source

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, Volume 13, Issue 53, 24 September 2026.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source

Active hair bundle movement under the otolithic membrane.

, 2013
(A)Traces of twitches in underlying hair bundles evoked by a series of 5 ms pulses delivered to the otolithic membrane in the excitatory (top) and inhibitory (bottom) directions.
Lea Fredrickson-Hemsing (328363), Clark Elliott Strimbu (328362), Dolores Bozovic (328364)   +2 more
core   +1 more source

Comparative Cochlear–Vestibular Aging Reveals Age‐Aligned Mitochondrial Ultrastructural Burden, Mitophagy–Autophagy Remodeling, Synaptic Uncoupling, and Sensory Functional Decline

Aging Cell, Volume 25, Issue 7, July 2026.
This study maps age‐aligned cochlear and vestibular decline in SAMP8 mice, linking functional impairment with synaptic vulnerability, mitochondrial ultrastructural injury, and autophagy/mitophagy–lysosome transcriptional remodeling. The findings provide an integrated framework for understanding shared inner‐ear aging trajectories.
Jingyi Xie, Xujia Zhang, Jinyi Tian, Yulu Yan, Ke Shi, Yongqi Pan, Yanni Zhang, Zichen Chen, Jianbin Sun, Hui Lv, Jingguo Chen, Xiaoyong Ren, Teru Kamogashira, Xiaotong Zhang, Ying Gao   +14 more
wiley   +1 more source

Early synapsids neurosensory diversity revealed by CT and synchrotron scanning

The Anatomical Record, Volume 309, Issue 4, Page 912-929, April 2026.
Abstract Non‐mammaliaform synapsids (NMS) represent the closest relatives of today's mammals among the early amniotes. Exploring their brain and nervous system is key to understanding how mammals evolved. Here, using CT and Synchrotron scanning, we document for the first time three extreme cases of neurosensory and behavioral adaptations that probe ...
J. Benoit, R. Araujo, E. S. Lund, A. Bolton, T. Lafferty, Z. Macungo, V. Fernandez   +6 more
wiley   +1 more source

Membrane fouling in osmotically driven membrane processes: A review

, 2016
The utilization of osmosis for engineered applications sparked off various emerging technologies relying on osmotically driven membrane processes (ODMPs).
Fane, Anthony Gordon, Tang, C, She, Q, Wang, Rong, She, Qianhong, Tang, Chuyang Y., Wang, R, Fane, AG   +7 more
core   +1 more source

Brain Morphology and Quantitative Assessment of Sensory Brain Areas in Southern Bluefin Tuna, Thunnus maccoyii (Scombridae, Teleostei)

Journal of Comparative Neurology, Volume 534, Issue 4, April 2026.
The absolute and relative volume of major sensory and integrative brain regions of the southern bluefin tuna Thunnus maccoyii are examined using magnetic resonance imaging (MRI). A dominant cerebellum projects into the midbrain ventricular space, while the optic tectum represents a smaller proportion of total brain volume than previously estimated ...
Myoung Hoon Ha, Lucille Chapuis, Rebecca Glarin, Bradford Moffat, David K. Wright, Travis L. Dutka, Julian Pepperell, Caroline C. Kerr, Kara E. Yopak, Shaun P. Collin   +9 more
wiley   +1 more source

Electrical Control of the Transduction Channels’ Gating Force in Mechanosensory Hair Cells

Advanced Science, Volume 13, Issue 16, 18 March 2026.
The inner ear's hair cells rely on mechanosensitive ion channels to convert vibrations of their hair‐bundle into electrical signals. We show that varying the electrical potential (U) across the sensory epithelium modulates a key determinant of mechanosensitivity—the gating force (FG)—by modulating the gating swing (d), ranging from the size of the ...
Achille Joliot, Laure Stickel, Pascal Martin   +2 more
wiley   +1 more source

Solubilization of lipids and membrane proteins into nanodiscs: Mode of action and applications of SMA copolymers [PDF]

, 2016
Cell membranes separate the inside and outside of cells. Membrane proteins in the cell membrane control the traffic of molecules across the membrane and are therefore targets for a lot of drugs: about 50 % of all approved drugs target a membrane protein!
Scheidelaar, S., Sub Membrane Biochemistry & Biophysics, Membrane Biochemistry and Biophysics   +2 more
core  

Observation of curative effect of modified canalith reposition on 48 cases with benign paroxysmal positional vertigo

Chinese Journal of Contemporary Neurology and Neurosurgery, 2012
Objective To investigate the therapeutic efficacy of the canalith repositioning maneuver in benign paroxysmal positional vertigo (BPPV). Methods The modified Epley procedure, Semont maneuver and Barbecue maneuver were applied in 48 cases of BPPV ...
Jun LAN
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