Recording potentials from scala media, saccule and utricle in mice [PDF]
To describe a protocol for recording electrical potentials from the scala media, saccule, and utricle in mice.CBA/J mice were used and potentials were recorded with glass electrodes inserted through the basilar membrane using a patch clamp system.Resting potentials were successfully recorded from the scala media, saccule and utricle using described ...
Huizhan Liu, Lidong Zhao
exaly +4 more sources
Vestibular Evoked Myogenic Potentials (cVEMP and oVEMP) in Pregnancy: A Clinical Study [PDF]
Background/Objectives: Pregnancy involves significant hormonal, cardiovascular, and physiological shifts that may potentially affect the vestibular system.
Isil Cakmak Karaer, Erdinc Sarıdogan
doaj +2 more sources
The segregation of Calb1, Calb2, and Prph neurons reveals distinct and mixed neuronal populations and projections to hair cells in the inner ear and central nuclei. [PDF]
Three populations of hair cells have a distinct expression of Calb1 and Calb2. (A, A′D) The central is highly positive for Calb1 while surrounding HC are positive for Calb2. Later, a calyx forms primarily with Calb1. (B, B′, D′, D″) Saccule and utricle start out positive for Calb2 but will upregulate the Calb1 in the striola that is primarily forming ...
Lee JH +6 more
europepmc +2 more sources
Comparative Cochlear-Vestibular Aging Reveals Age-Aligned Mitochondrial Ultrastructural Burden, Mitophagy-Autophagy Remodeling, Synaptic Uncoupling, and Sensory Functional Decline. [PDF]
This study maps age‐aligned cochlear and vestibular decline in SAMP8 mice, linking functional impairment with synaptic vulnerability, mitochondrial ultrastructural injury, and autophagy/mitophagy–lysosome transcriptional remodeling. The findings provide an integrated framework for understanding shared inner‐ear aging trajectories.
Xie J +14 more
europepmc +2 more sources
Binocular 3D otolith-ocular reflexes: responses of chinchillas to prosthetic electrical stimulation targeting the utricle and saccule [PDF]
From animal experiments by Cohen and Suzuki et al. in the 1960s to the first-in-human clinical trials now in progress, prosthetic electrical stimulation targeting semicircular canal branches of the vestibular nerve has proven effective at driving directionally appropriate vestibulo-ocular reflex eye movements, postural responses, and perception.
Margaret R Chow +2 more
exaly +3 more sources
Vestibular Evoked Myogenic Potentials Reveal Impairments in Vestibular Nerve Pathways in Children with Attention Deficit Hyperactivity Disorder [PDF]
Objective: This study aims to analyze the characteristics of vestibular evoked myogenic potentials (VEMPs) and evaluate specific vestibular nerve pathway impairments in children with Attention Deficit Hyperactivity Disorder (ADHD) compared to typically ...
Dekun Gao +3 more
doaj +2 more sources
Developmental Expression of Membrane Pumps and Ion Channels in Human Vestibular Endolymph Homeostasis. [PDF]
ABSTRACT The expression patterns of key membrane pumps and ion channels involved in endolymph cycling have been studied in the rodent inner ear and the developing and adult human cochlea. However, little is known about their expression during the development of the human vestibular system.
van Beelen ESA +4 more
europepmc +2 more sources
Endolymphatic hydrops features excess endolymph in the membranous labyrinth, and is a marker of Menière's disease. Between the early 1980s and late 2000s, MRI in Menière's disease aimed purely to rule out tumor or malformation as differential diagnoses for the pressure disorder.
Arnaud Attye, Michael Eliezer
exaly +5 more sources
First evolutionary insights into the human otolithic system [PDF]
The human otolithic system (utricle and saccule), housed within the bony vestibule of the inner ear, establishes our sense of balance in conjunction with the semicircular canals.
Christopher M. Smith +4 more
doaj +2 more sources
The distinction between sensory inputs that are a consequence of our own actions from those that result from changes in the external world is essential for perceptual stability and accurate motor control. In this study, we investigated whether linear translations are encoded similarly during active and passive translations by the otolith system ...
Mohsen Jamali +2 more
exaly +4 more sources

