Results 21 to 30 of about 3,411 (176)
Epithelial cell stretching and luminal acidification lead to a retarded development of stria vascularis and deafness in mice lacking pendrin. [PDF]
PLoS ONE, 2011 Loss-of-function mutations of SLC26A4/pendrin are among the most prevalent causes of deafness. Deafness and vestibular dysfunction in the corresponding mouse model, Slc26a4(-/-), are associated with an enlargement and acidification of the membranous ...
Hyoung-Mi Kim, Philine Wangemann
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Frontiers in Surgery, 2021 Background: The etiology of Meniere's disease (MD) and endolymphatic hydrops believed to underlie its symptoms remain unknown. One reason may be the exceptional complexity of the human inner ear, its vulnerability, and surrounding hard bone.
Hao Li +7 more
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Advances in otolith-related protein research
Frontiers in Neuroscience, 2022 Otoliths are biological crystals formed by a layer of calcium carbonate crystal that adhere to the ciliary surface of the utricular and saccular receptors in the vestibule of all vertebrates inner ear, enabling the utricle and saccule to better perceive ...
Shouju Huang, Shouju Huang, Shuxia Qian
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, 2023 Background The aqeductus vestibuli (aqueduct) is believed to connect to the saccule in embryos and adults. However, in embryos, the saccule and utricle are known to communicate widely to provide a common endolymph space “atrium”.
Kawase, Tetsuaki +13 more
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Quantitative assessment of inner ear variation in elasmobranchs
Scientific Reports, 2023 Considerable diversity has been documented in most sensory systems of elasmobranchs (sharks, rays, and skates); however, relatively little is known about morphological variation in the auditory system of these fishes.
Derek J. Sauer +3 more
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Effectiveness of Virtual Reality Therapy in the Rehabilitation of Isolated Otolith Dysfunction [PDF]
Zagazig University Medical JournalBackground: Previous studies have shown virtual reality (VR) therapy to effectively manage vestibular dysfunction. However, its effectiveness in managing patients specifically diagnosed with Isolated Otolith Dysfunction (IOD) lacks comprehensive ...
Reem Elbeltagy, Rania Alkahtani
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Scientific Reports, 2021 Intravenous gadolinium-enhanced inner-ear magnetic resonance imaging (IV-Gd inner-ear MRI) has been used to visualize endolymphatic hydrops (EH) in clinical diagnosis of Ménière’s disease (MD).
Young Sang Cho +7 more
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Degeneration of saccular hair cells caused by MITF gene mutation
Neural Development, 2019 Background Waardenburg syndrome (WS) is the consequence of an inherited autosomal dominant mutation which causes the early degeneration of intermediate cells of cochlear stria vascularis (SV) and profound hearing loss.
Yi Du +9 more
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Hair Cell Heterogeneity in the Goldfish Saccule [PDF]
, 1995 A set of cytological studies performed in the utricle and saccule of Astronotus ocellatus (Teleostei, Percomorphi, Cichlidae) identified two basic types of hair cells and others with some intermediate characteristics.
Lanford, Pamela J. +7 more
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Uneven Effects of Sleep Apnea on Semicircular Canals and Otolithic Organs
Frontiers in Neurology, 2022 ObjectiveThis study aimed to explore how obstructive sleep apnea (OSA) affects the function of each vestibular organ and to identify the correlations among them.MethodsA prospective study was conducted involving 32 healthy controls and 64 patients with ...
Xin-Da Xu +12 more
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