Results 21 to 30 of about 2,948 (142)

Vestibular modulation of muscle sympathetic nerve activity during sinusoidal linear acceleration in supine humans

open access: yesFrontiers in Neuroscience, 2014
The utricle and saccular components of the vestibular apparatus detect linear displacements of the head in the horizontal and vertical planes, respectively. We previously showed that sinusoidal linear acceleration in the horizontal plane of seated humans
Elie eHammam   +5 more
doaj   +1 more source

Validation of inner ear MRI in patients with Ménière’s disease by comparing endolymphatic hydrops from histopathologic specimens

open access: yesScientific Reports, 2021
Intravenous gadolinium-enhanced inner-ear magnetic resonance imaging (IV-Gd inner-ear MRI) has been used to visualize endolymphatic hydrops (EH) in clinical diagnosis of Ménière’s disease (MD).
Young Sang Cho   +7 more
doaj   +1 more source

Degeneration of saccular hair cells caused by MITF gene mutation

open access: yesNeural Development, 2019
Background Waardenburg syndrome (WS) is the consequence of an inherited autosomal dominant mutation which causes the early degeneration of intermediate cells of cochlear stria vascularis (SV) and profound hearing loss.
Yi Du   +9 more
doaj   +1 more source

Uneven Effects of Sleep Apnea on Semicircular Canals and Otolithic Organs

open access: yesFrontiers in Neurology, 2022
ObjectiveThis study aimed to explore how obstructive sleep apnea (OSA) affects the function of each vestibular organ and to identify the correlations among them.MethodsA prospective study was conducted involving 32 healthy controls and 64 patients with ...
Xin-Da Xu   +12 more
doaj   +1 more source

Inner ear morphology in the Atlantic molly Poecilia mexicana--first detailed microanatomical study of the inner ear of a cyprinodontiform species. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Fishes show an amazing diversity in hearing abilities, inner ear structures, and otolith morphology. Inner ear morphology, however, has not yet been investigated in detail in any member of the diverse order Cyprinodontiformes.
Tanja Schulz-Mirbach   +2 more
doaj   +1 more source

The Growing Evidence for the Importance of the Otoliths in Spatial Memory

open access: yesFrontiers in Neural Circuits, 2019
Many studies have demonstrated that vestibular sensory input is important for spatial learning and memory. However, it has been unclear what contributions the different parts of the vestibular system – the semi-circular canals and otoliths – make to ...
Paul F. Smith   +2 more
doaj   +1 more source

Membrane Stress in the Human Labyrinth and Meniere Disease: A Model Analysis

open access: yesInternational Archives of Otorhinolaryngology, 2015
Introduction The nature and extent of membrane damage encountered in Meniere disease remains unexplained. Pressure-induced membrane stress may underlie the characteristic hydropic distention.
Daniel J. Pender
doaj   +1 more source

Role of SoxE transcription factors in development and disease

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Acute histological reactions in the otolith organs to inner ear drug delivery through a cochlear implant

open access: yesFrontiers in Neurology
IntroductionCochlear implantation is currently regarded as a safe and minimally invasive procedure. However, cochlear implantation can have an impact on vestibular function, despite the lack of correlation between patient symptomatology and damage in ...
Raquel Manrique-Huarte   +3 more
doaj   +1 more source

Labyrinthine Abnormalities on MRI in Untreated Otosclerosis: Prevalence and Clinical Relevance

open access: yesThe Laryngoscope, Volume 136, Issue 8, Page 3559-3568, August 2026.
In untreated otosclerosis with labyrinthine symptoms, delayed 3D FLAIR MRI rarely demonstrates endolymphatic hydrops but frequently reveals blood–labyrinth barrier (BLB) disruption. BLB enhancement is spatially associated with cochlear endosteal and round window involvement and increases with the severity of the hearing loss phenotype.
Héléna Pencroffi   +7 more
wiley   +1 more source

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