Results 51 to 60 of about 23,782 (178)

Molecular Biomarkers in Meniere's Disease: A Scoping Review of Current Evidence

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Meniere's disease is a complex chronic inner ear condition that is characterized by vertigo, tinnitus, aural fullness, and progressive hearing loss. Currently, diagnostic strategies remain symptom‐driven, and treatments focus on management of discrete episodes rather than targeting underlying pathophysiology.
Hamza Kamran, Zaharadeen Jimoh, Tariq Issa, Nahla A. Gomaa   +3 more
wiley   +1 more source

Fibrous Biomaterial Scaffold for Tympanic Membrane Repair: Microarchitectural Engineering and Structure Function Performance

Journal of Functional Biomaterials
Tympanic membrane (TM) perforations, arising from infections, injuries, or chronic otitis media, remain a frequent clinical finding and can lead to hearing problems when the tissue does not regenerate adequately.
Lea Jiang, Chokri Cherif, Michael Wöltje   +2 more
doaj   +1 more source

Type I Tympanoplasty

B-ENT, 2022
When an ENT surgeon plans on starting the endoscopic technique for ear surgery, type I tympanoplasty is the first intervention to master. We wish to discuss the advantages and difficulties of the use of the endoscope, and offer a description of type I ...
Jolien Euben, Sandrine Machiels, Nicolas Mardyla   +2 more
doaj  

CRISPR screening identifies the deubiquitylase ATXN3 as a PD-L1–positive regulator for tumor immune evasion

The Journal of Clinical Investigation, 2023
Regulation of tumoral PD-L1 expression is critical to advancing our understanding of tumor immune evasion and the improvement of existing antitumor immunotherapies.
Shengnan Wang, Radhika Iyer, Xiaohua Han, Juncheng Wei, Na Li, Yang Cheng, Yuanzhang Zhou, Qiong Gao, Lingqiang Zhang, Ming Yan, Zhaolin Sun, Deyu Fang   +11 more
doaj   +1 more source

Cost‐Effectiveness of Canal Wall Up Tympanoplasty With and Without Obliteration in Cholesteatoma Surgery

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To determine the cost‐effectiveness of the bony obliteration tympanoplasty compared with canal wall up without obliteration in cholesteatoma surgery from a healthcare payer perspective. Study design State‐transition Markov model. Setting Tertiary care center in the Netherlands. Methods A state‐transition Markov model was developed to
Tom R. von Hebel, Martijn A. H. Oude Voshaar, Steven W. Mes, Bernd Kremer, Robert J. Pauw, Hylke F. E. van der Toom   +5 more
wiley   +1 more source

Removal of a Wire Brush Bristle from the Hypopharynx Using Suspension, Microscope, and Fluoroscopy

Case Reports in Otolaryngology, 2015
Wire brush bristles are an increasingly recognized hazard that can present as a foreign body in the aerodigestive tract. Due to their small size and tendency to become embedded in surrounding tissue, these small metallic bristles present a unique ...
Matthew R. Naunheim, Matthew M. Dedmon, Matthew C. Mori, Ahmad R. Sedaghat, Jayme R. Dowdall   +4 more
doaj   +1 more source

Clinical Application of the SAMEO‐ATO Classification and Analysis of the Correlation Between Individual Subgroups and Surgery Duration

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Tympanomastoid surgery, encompassing intricate middle ear and mastoid procedures, necessitates a standardized classification system to ensure consistent documentation, enhance comparability, and improve outcome analysis across different clinical settings.
Julia van de Loo, Naledi Jankowski, Marcel Mayer, Hans Eckel, Louis Jansen, Helen Abing, Anne Nobis, Johannsen Jannik, Jens Peter Klußmann, Jan Christoffer Lüers   +9 more
wiley   +1 more source

Functional results of revision canal wall down mastoidectomy

Journal of Bio-X Research, 2019
. In this retrospective study, we evaluated the preoperative and intraoperative findings and functional results of revision surgery after canal wall down mastoidectomy.
Jun Lv, He Li, Xianmin Wu, Xiaoyun Chen, Yideng Huang   +4 more
doaj   +1 more source

Speech Recognition Deficits in Presbyacusis: Links to Cortical Structural and Functional Alterations

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To characterize speech recognition in presbyacusis and its associated neurophysiological and cortical structural features, and to explore structure‐function‐behavior relationships within the presbyacusis phenotype. Methods Thirty elderly patients with presbyacusis(HI) and thirty‐three healthy young controls(NH) completed a behavioral
Xiao‐Qian Ren, Lan Lan, Xiao‐Long Li, Xiang‐Bing Bian, Jin Li, Lan Yu, Dan‐Yang Li, Xin Lou, Qiu‐Ju Wang   +8 more
wiley   +1 more source

Caspase-Mediated Apoptosis in the Cochleae Contributes to the Early Onset of Hearing Loss in A/J Mice

ASN Neuro, 2015
A/J and C57BL/6 J (B6) mice share a mutation in Cdh23 ( ahl allele) and are characterized by age-related hearing loss. However, hearing loss occurs much earlier in A/J mice at about four weeks of age.
Xu Han, Ruli Ge, Gang Xie, Ping Li, Xin Zhao, Lixiang Gao, Heng Zhang, Oumei Wang, Fei Huang, Fengchan Han   +9 more
doaj   +1 more source