Results 11 to 20 of about 2,602 (246)

Single-cell spatial transcriptomics reveals potential molecular mechanisms of <i>Abelmoschus manihot</i> (L.) medic in treating diabetic kidney disease. [PDF]

open access: yesImeta
A clinical study reported that Abelmoschus manihot (L.) Medic (A. manihot), in the form of Huangkui capsule (HKC), combined with irbesartan (IRB) is an effective therapy for patients with diabetic kidney disease (DKD). The bioactive components of HKC are total flavones extracted from A. manihot (TFA).
Wu C   +7 more
europepmc   +2 more sources

Brain response in asthma: the role of “lung-brain” axis mediated by neuroimmune crosstalk

open access: yesFrontiers in Immunology, 2023
In addition to typical respiratory symptoms, patients with asthma are frequently accompanied by cognitive decline, mood disorders (anxiety and depression), sleep disorders, olfactory disorders, and other brain response manifestations, all of which worsen
Yao Wang   +23 more
doaj   +1 more source

Tumor necrosis factor-α mediated inflammation versus apoptosis in age-related hearing loss

open access: yesFrontiers in Aging Neuroscience, 2022
An almost universal phenomenon occurring during aging is a state of chronic, low-grade, sterile inflammation. Inflammation is a crucial contributor to various age-related pathologies and natural processes in aging tissues. Tumor necrosis factor-α (TNF-α),
Ting Wu   +15 more
doaj   +1 more source

Identification of a lncRNA AC011511.5- Mediated Competitive Endogenous RNA Network Involved in the Pathogenesis of Allergic Rhinitis

open access: yesFrontiers in Genetics, 2022
LncRNA-miRNA-mRNA competing endogenous RNA (ceRNA) networks are thought to be involved in regulating the development of various inflammatory diseases. Up to now, the mechanism of such a network in allergic rhinitis (AR) remains unclear.
Yujuan Yang   +19 more
doaj   +1 more source

Case Report: Two cases of survival after complete transection of the left common carotid artery

open access: yesFrontiers in Surgery, 2023
Penetrating carotid artery traumas are rare yet fatal injuries with a high rate of mortality, and survivors may live with neurological sequelae. Of all the types of penetrating carotid artery traumas, the total transection of the common carotid artery ...
Xin Yang   +18 more
doaj   +1 more source

Identification and verification of eight cancer-associated fibroblasts related genes as a prognostic signature for head and neck squamous cell carcinoma

open access: yesHeliyon, 2023
Cancer-associated fibroblasts (CAFs) can exert their immunosuppressive effects by secreting various effectors that are involved in the regulation of tumor-infiltrating immune cells as well as other immune components in the tumor immune microenvironment ...
Lei Dong   +6 more
doaj   +1 more source

Identification and Validation of 17-lncRNA Related to Regulatory T Cell Heterogeneity as a Prognostic Signature for Head and Neck Squamous Cell Carcinoma

open access: yesFrontiers in Immunology, 2021
Successful eradication of tumors by the immune system depends on generation of antigen-specific T cells that migrate to tumor sites and kill cancerous cells. However, presence of suppressive Treg populations inside tumor microenvironment hinders effector
Qi Sun   +13 more
doaj   +1 more source

Network pharmacology analysis and experimental verification reveal the mechanism of the traditional Chinese medicine YU-Pingfeng San alleviating allergic rhinitis inflammatory responses

open access: yesFrontiers in Plant Science, 2022
YU-Pingfeng San (YPFS) can regulate inflammatory response to alleviate the symptoms of nasal congestion and runny rose in allergic rhinitis (AR). However, the mechanism of action remains unclear.
Zhen Liu   +21 more
doaj   +1 more source

Subcutaneous emphysema with pneumomediastinum after elective tonsillectomy - Case study

open access: yesOtolaryngology Case Reports, 2021
Tonsillectomy is a common operation in otorhinolaryngology with subcutaneous emphysema with pneumomediastinum being an uncommon, nevertheless, potentially life-threatening complication.
Dimitrios Paouris   +2 more
doaj   +1 more source

Laryngeal extra-skeletal Ewing sarcoma treated with DC-CTL immunotherapy: A case report and review of the literature

open access: yesFrontiers in Oncology, 2022
Extra-skeletal Ewing sarcoma (EES) is a rare sarcoma composed primarily of small round cells, capable of metastasizing and relapsing. Few cases of EES originating from the larynx have been reported, and no publications regarding laryngeal EES treated ...
Hanrui Wang   +19 more
doaj   +1 more source

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