Results 61 to 70 of about 477,365 (186)

Single‐cell spatial transcriptomics reveals potential molecular mechanisms of Abelmoschus manihot (L.) medic in treating diabetic kidney disease

open access: yesiMeta, Volume 4, Issue 6, December 2025.
A clinical study reported that Abelmoschus manihot (L.) Medic (A. manihot), in the form of Huangkui capsule (HKC), combined with irbesartan (IRB) is an effective therapy for patients with diabetic kidney disease (DKD). The bioactive components of HKC are total flavones extracted from A. manihot (TFA).
Chenhua Wu   +7 more
wiley   +1 more source

Breathing straws [PDF]

open access: yes, 2017
Following nasal, septal or endoscopic surgery, it is common practice to insert nasal packs in both nasal cavities to achieve haemostasis, if there has been any bleeding at the end of the procedure.
Briner, H R., Dhanasekar, G., Simmen, D.
core  

Paediatric otorhinolaryngology, head and neck emergencies at a Tertiary Health Care Centre in Nigeria [PDF]

open access: yes, 2020
Background: Paediatric otorhinolaryngology emergency is a common disorder worldwide which is poorly reported in most developing countries like Nigeria.
Adegbiji , W.A.   +4 more
core   +1 more source

Predictive Value of Blood Eosinophil Ratio for Risk Stratification in Patients With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

open access: yesLaryngoscope Investigative Otolaryngology, Volume 10, Issue 6, December 2025.
ABSTRACT Background Eosinophilic chronic rhinosinusitis with nasal polyps (ECRSwNP) is associated with severe symptoms and poor outcomes, but the diagnostic criteria remain elusive. The objective of this study is to identify preoperative predictors of ECRSwNP using multiple diagnostic thresholds and to propose a clinically actionable risk ...
Ting Zuo   +7 more
wiley   +1 more source

Prophylactic administration of haloperidol plus midazolam reduces postoperative nausea and vomiting better than using each drug alone in patients undergoing middle ear surgery

open access: yesSaudi Journal of Anaesthesia, 2012
Aims: The efficacy of using midazolam or haloperidol for prevention of postoperative nausea and vomiting (PONV) has been investigated before. The main object of the present study was to evaluate the anti-emetic effects of combining administration of ...
Azim Honarmand   +3 more
doaj   +1 more source

Taste and Smell Disorders in Children and Young Adults With Cystic Fibrosis and Primary Ciliary Dyskinesia—A Prospective Comparative Study

open access: yesPediatric Pulmonology, Volume 60, Issue 12, December 2025.
ABSTRACT Background In cystic fibrosis (CF), the defect of the CF transmembrane conductance regulator (CFTR) can also affect sensory nerve cell function, as recently demonstrated in animal models. The aim of this prospective cohort study was to investigate whether taste and smell disorders in CF correlate with persistent CFTR dysfunction detectable by ...
Lea Christiane Beermann   +9 more
wiley   +1 more source

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, Volume 12, Issue 40, October 27, 2025.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin   +9 more
wiley   +1 more source

Teleoperated Magnetic Endoscopy: A Case Study and Perspective

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 10, October 2025.
This perspective highlights the recent research efforts in robotic magnetic platforms for telesurgery and their translation to clinical settings for endoscopic procedures. To demonstrate this approach, this work also introduces an in vivo gastroscopy performed in a porcine model, during which an operator in Zurich, Switzerland, successfully controls a ...
Alexandre Mesot   +8 more
wiley   +1 more source

Investigating the mechanisms of capsicum in age‐related hearing loss: Based on network pharmacology

open access: yesEye &ENT Research, Volume 2, Issue 3, Page 202-214, September 2025.
Abstract Background To explore the material basis and action mechanism of the chemical component gene of pepper on presbycusis, and to provide a reference for the traditional Chinese medicine treatment of age‐related hearing loss (ARHL). Methods The chemical composition and action targets of traditional Chinese medicine flavor of pepper were searched ...
Yan Wang   +9 more
wiley   +1 more source

Breast cancer robotic nipple sparing mastectomy: evaluation of several surgical procedures and learning curve

open access: yesWorld Journal of Surgical Oncology, 2019
BackgroundFew studies of robotic nipple sparing mastectomy (NSM) were reported. We report feasibility of robotic NSM and determine standard surgical procedure and learning curve threefold.MethodsA cohort of patients with robotic NSM for breast cancer was
G. Houvenaeghel   +7 more
semanticscholar   +1 more source

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