Results 71 to 80 of about 477,365 (186)

Patient's Perspective and Change in Quality of Life After Stapes Surgery: A Multicenter Prospective Trial

open access: yesOtolaryngology–Head and Neck Surgery, Volume 173, Issue 3, Page 697-704, September 2025.
Abstract Objective This study evaluated outcomes of stapes surgery in otosclerosis patients by assessing audiometric results and health‐related quality of life (HRQOL) using the Dutch Stapesplasty Outcome Test‐25 (SPOT‐25) questionnaire. Additionally, the role of SPOT‐25 in preoperative decision‐making and as a follow‐up tool was explored.
Maaike Jellema   +7 more
wiley   +1 more source

The Clinical Significance of the Primary Malignant Melanoma of the Lower Respiratory Tract and/or Lung Based on the Analysis of Published Case Reports and of Two Patients [PDF]

open access: yes, 1995
Considering the data and including two patients of the authors, there exist only 18 authentic cases of primary malignant melanoma of the lower respiratory tract and/or the lung.
Barzó, P.   +3 more
core   +3 more sources

Glass‐blowing, brass‐playing, and other laryngocele etiologies: Fact or fiction? A systematic literature review

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 11, Issue 3, Page 468-476, September 2025.
Abstract Objective Laryngocele is a rare condition, which can be congenital or acquired, characterized by an abnormal dilatation of the laryngeal ventricle filled with air. A correlation between laryngocele formation and increased intralaryngeal pressure has been postulated, as much as a frequent coexistence with laryngeal carcinoma.
Giorgia Pugliese   +8 more
wiley   +1 more source

Surgical Experiences of Patients From the Circumpolar North: A Scoping Review

open access: yesWorld Journal of Surgery, Volume 49, Issue 9, Page 2512-2522, September 2025.
The Circumpolar North is an expansive region that includes the northernmost parts of the Earth, extending across the Arctic and Subarctic zones. This area, characterized by its geographical remoteness, harsh climate, limited healthcare infrastructure, and diverse patient population, creates unique challenges for the provision and delivery of surgical ...
Jillian Schneidman   +5 more
wiley   +1 more source

Mucopolysaccharidoses : otorhinolaryngologic manifestations and management [PDF]

open access: yes, 2017
Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2017The mucopolysaccharidoses (MPS) belong to a group of rare lysosomal storage diseases and are caused by a deficiency in enzymes involved in the ...
Portugal, Ana Rita Duarte Serejo Alcobia
core  

Diagnostic Accuracy of an Orofacial Scale for the Detection of Orofacial Myofunctional Disorders in Patients With Obstructive Sleep Apnoea

open access: yesJournal of Oral Rehabilitation, Volume 52, Issue 9, Page 1343-1350, September 2025.
ABSTRACT Background Patients with obstructive sleep apnoea (OSA) are known to have orofacial myofunctional disorders (OMD) compared to healthy individuals. Consequently, treatment with oropharyngeal exercises has shown promise in some OSA cases. However, this requires an adequate orofacial myofunctional evaluation.
Gislaine Aparecida Folha   +2 more
wiley   +1 more source

SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy

open access: yesAdvanced Science, Volume 12, Issue 31, August 21, 2025.
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong   +9 more
wiley   +1 more source

Totally implantable middle ear device for rehabilitation of sensorineural hearing loss: preliminary experience with the Esteem†, Envoy [PDF]

open access: yes, 2009
Conclusion. According to the first series of implanted patients, Esteem 2† technology can be regarded as a safe and reliable system for hearing restoration in case of moderate to severe sensorineural hearing loss. Objectives.
BARBARA, Maurizio   +2 more
core   +1 more source

Cocleostomia transcanal: resultados em longo prazo de um estudo de coorte Transcanal cochleostomy in cochlear implant surgery: long-term results of a cohort study

open access: yesBrazilian Journal of Otorhinolaryngology, 2012
A técnica de acesso combinado (TAC) ao implante coclear (IC) é uma variação da técnica clássica de mastoidectomia e timpanotomia posterior (MPTA). A TAC combina um acesso transcanal à cocleostomia com uma timpanotomia posterior reduzida para a inserção ...
Michelle Lavinsky-Wolff   +5 more
doaj   +1 more source

Transforming Growth Factor‐β Pathway: Biological Functions and Therapeutic Targets

open access: yesMedComm, Volume 6, Issue 7, July 2025.
Natural compounds modulate the TGF‐β pathway, which acts as both a tumor suppressor and promoter during cancer progression. Agents such as ginsenosides, halofuginone, and EGCG influence cell proliferation, apoptosis, and angiogenesis. These bioactive molecules may complement standard therapies, highlighting the need for advanced formulations ...
Reham Hassan Mekky   +9 more
wiley   +1 more source

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