Results 51 to 60 of about 121,002 (293)

CNTN2 Deficiency Disrupts Ascending Auditory Neuroglial Interactions and Redox Homeostasis in Neural Presbycusis

open access: yesAdvanced Science, EarlyView.
. ABSTRACT Neural presbycusis disrupts auditory timing and speech perception, yet its molecular basis remains poorly understood. This study identifies Cntn2 as the Ranvier's nodal molecule significantly downregulated in aged auditory nerves. Cntn2 heterozygous knockout (Cntn2+/−) mice showed elevated auditory brainstem response thresholds and prolonged
Penghui Chen   +8 more
wiley   +1 more source

Physiological care for the mucosa of the nose: prevention of ARVI

open access: yesМедицинский совет, 2019
The article highlights the role and place of elimination and irrigation therapy in the treatment and prevention of acute respiratory infections in children.
N. E. Payganova, Kh. Sh. Davudov
doaj   +1 more source

Otolaryngology Residents’ Attitudes, Experiences, and Barriers Regarding the Medical Research

open access: yesTurkish Archives of Otorhinolaryngology, 2021
Objective:It was aimed to investigate the attitudes, experiences, and barriers towards scientific research among otolaryngology residents in Turkey.Methods:Anonymous data were collected via an online survey. The demographic characteristics and experience
Hülya Eyigör, Cüneyt Orhan Kara
doaj   +1 more source

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

open access: yesAdvanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao   +6 more
wiley   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

open access: yesAdvanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale   +23 more
wiley   +1 more source

The attitude of medical students towards otorhinolaryngology

open access: yes, 2014
Background: Otorhinolaryngology is under-represented in most undergraduate curricula. This work aims to determine the interest and attitude of medical students towards otorhinolaryngology both as a contribution to medical practice and as a specialty ...
Nimkur, TI, Yaro, JP, Adoga, AA
core   +1 more source

Image-Guided Otorhinolaryngology [PDF]

open access: yes, 2013
Beginning with a brief historical background, the chapter then offers the reader a practical overview of established procedures using image-guided surgery (IGS) in otorhinolaryngology.
Dubach, Patrick   +7 more
core   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

open access: yesAdvanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen   +11 more
wiley   +1 more source

The Role of Seawater and Saline Solutions in Treatment of Upper Respiratory Conditions

open access: yesMarine Drugs, 2022
The history of saline nasal irrigation (SNI) is indeed a long one, beginning from the ancient Ayurvedic practices and gaining a foothold in the west at the beginning of the 20th century.
Danijela Štanfel   +6 more
doaj   +1 more source

Division of tongue tie: review of practice through a tertiary paediatric otorhinolaryngology service.

open access: yes, 2012
Recent NICE guidance declared that evidence regarding surgical division of tongue tie was adequate to support the use of the procedure, provided that normal arrangements are in place for consent, audit and clinical governance.
Colreavy, M   +3 more
core   +1 more source

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