Results 11 to 20 of about 15,368 (252)

Bisphosphonate therapy in otosclerosis: A scoping review

Laryngoscope Investigative Otolaryngology, 2022
Objective Otosclerosis, a leading cause of deafness in adults, results from defective bone remodeling of the otic capsule. Bisphosphonates have been used to decrease bone remolding in many diseases, including otosclerosis.
René E. Zimmerer, Robert E. Africa, Zack K. Westenhaver, Brian J. McKinnon   +3 more
doaj   +2 more sources

Genome-wide screen of otosclerosis in population biobanks: 27 loci and shared associations with skeletal structure

Nature Communications, 2023
Otosclerosis is a common form of hearing loss, with an unclear genetic etiology. Here, the authors perform a genome-wide association study meta-analysis of otosclerosis identifying 27 genetic loci, pointing to genes involved in bone remodeling, skeletal ...
Joel T. Rämö, Tuomo Kiiskinen, Richard Seist, Kristi Krebs, Masahiro Kanai, Juha Karjalainen, Mitja Kurki, Eija Hämäläinen, Paavo Häppölä, Aki S. Havulinna, Heidi Hautakangas, FinnGen, Reedik Mägi, Priit Palta, Tõnu Esko, Andres Metspalu, Matti Pirinen, Konrad J. Karczewski, Samuli Ripatti, Lili Milani, Konstantina M. Stankovic, Antti Mäkitie, Mark J. Daly, Aarno Palotie   +23 more
doaj   +2 more sources

Imaging Studies in Otosclerosis: An Up-to-date Comprehensive Review

International Archives of Otorhinolaryngology, 2021
Introduction Otosclerosis is a primary osteodystrophy of the otic capsule, frequently responsible for acquired hearing loss in adults. Although the diagnostic value of imaging investigations in otosclerosis is debatable, they might still be employed with
Lucas Resende Lucinda Mangia, Luiz Otávio de Mattos Coelho, Bettina Carvalho, Adriana Kosma Pires de Oliveira, Rogerio Hamerschmidt   +4 more
doaj   +2 more sources

Brazilian Society of Otology task force – Otosclerosis: evaluation and treatment

Brazilian Journal of Otorhinolaryngology, 2023
Objectives: To review and provide evidence-based recommendations for the diagnosis and treatment of otosclerosis. Methods: Task force members were educated on knowledge synthesis methods, including electronic database search, review and selection of ...
Vagner Antonio Rodrigues Silva, Henrique Furlan Pauna, Joel Lavinsky, Guilherme Corrêa Guimarães, Nicolau Moreira Abrahão, Eduardo Tanaka Massuda, Melissa Ferreira Vianna, Cláudio Márcio Yudi Ikino, Vanessa Mazanek Santos, José Fernando Polanski, Maurício Noschang Lopes da Silva, André Luiz Lopes Sampaio, Raul Vitor Rossi Zanini, Luiz Fernando Manzoni Lourençone, Mariana Moreira de Castro Denaro, Daniela Bortoloti Calil, Carlos Takahiro Chone, Arthur Menino Castilho   +17 more
doaj   +2 more sources

Vertigo Associated with Otosclerosis and Stapes Surgery—A Narrative Review

Medicina, 2023
Otosclerosis is a pathological condition affecting the temporal bone, and is characterized by remodelling of the labyrinthine bone tissue through a dynamic process of osteolysis and osteogenesis.
Violeta Necula, Alma Aurelia Maniu, László-Péter Ujváry, Maximilian-George Dindelegan, Mara Tănase, Mihai Tănase, Cristina Maria Blebea   +6 more
doaj   +2 more sources

Assessment of Raftlin and blood count parameters in otosclerosis [PDF]

Frontiers in Neurology
ObjectiveAlthough otosclerosis is a common disease, its etiology has not yet been clearly elucidated. One of the factors recently implicated in its pathogenesis is chronic inflammation.
Duygu Erdem, Sultan Şevik Eliçora, Berrak Güven, Deniz Baklaci   +3 more
doaj   +2 more sources

Jacob's Syndrome and Hearing Loss: A Case Study. [PDF]

Clin Case Rep
Bilateral mild‐to‐moderate hearing loss identified in a child with Jacob’s syndrome (47,XYY). This case highlights the importance of early audiological assessment in children with chromosomal abnormalities to facilitate timely intervention and optimize developmental outcomes.
Bagheri H, Kouhi A, Alidoust M, Koravand A.   +3 more
europepmc   +2 more sources

Fabry disease presenting with sudden hearing loss and otosclerosis: a case report [PDF]

Journal of Medical Case Reports, 2012
Introduction Fabry disease is an X-linked lysosomal storage disorder resulting in a multiple-system disorder with a wide spectrum of physical signs and symptoms, predominantly affecting the central and peripheral nervous systems, skin, heart, kidneys ...
Felisati Giovanni, Salvatici Elisabetta, Pipolo Carlotta, Portaleone Sara, Riva Enrica, Giovannini Marcello   +5 more
doaj   +2 more sources

Learning Curve for CO₂ Laser Stapedotomy: A Single-Surgeon Experience in South Korea. [PDF]

Laryngoscope Investig Otolaryngol
This study defines the learning curve for CO2 laser‐assisted incus‐stapedotomy in a low‐volume East Asian setting. Using Bayesian and cumulative sum analyses of 100 consecutive cases, we identified a robust proficiency transition at approximately the 30th case.
Nam DW, Jeon H, Koo JW.
europepmc   +2 more sources

Investigation of Neutrophil-to-lymphocyte Ratio as a Biomarker to Evaluate Systemic Inflammation in Clinical Otosclerosis

İstanbul Medical Journal, 2019
Introduction:Otosclerosis with yet unexplained etiopathogenesis, especially for inflammatory mechanism, affects otic capsule of ear and causes progressive hearing loss.
Hasan Deniz Tansuker, Cemal Özyılmaz, Abdurrahman Buğra Cengiz, Mehmet Faruk Oktay   +3 more
doaj   +2 more sources