Results 101 to 110 of about 32,831 (248)

Olfactory proteomics reveals the capacity of the HDAC1 inhibitor pyroxamide to halt the α‐synuclein preformed fibrils‐induced damage in nasal epithelial, microglial and dopaminergic neuronal cell lines

Brain Pathology, EarlyView.
Omics‐driven drug repositioning reveals pyroxamide as a neuroprotective HDAC1 inhibitor in Parkinson's disease models. Abstract Parkinson's disease (PD) is the second most common neurodegenerative disorder mainly characterized by the degeneration of dopaminergic neurons originating in the substantia nigra (SN) pars compacta and projecting to other ...
Paz Cartas‐Cejudo, Marina De Miguel, Leire Extramiana, Mercedes Lachén‐Montes, Silvia Romero‐Murillo, Djordje Gveric, Joaquín Fernández‐Irigoyen, Enrique Santamaría   +7 more
wiley   +1 more source

Implementation strategies for early hand therapy for young children with cerebral palsy

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To select and prioritize implementation strategies for early hand therapy for children under 2 years old with suspected or confirmed cerebral palsy. Method This implementation study used a mixed‐methods sequential explanatory design guided by the Consolidated Framework for Implementation Research.
Alicia J Hilderley, Dejana Nikitovic, Darcy Fehlings, John Andersen, Eleanor Heptonstall, Christine Cassidy, Adam Kirton, The INTERPLAY Study Team   +7 more
wiley   +1 more source

International Occupational Therapists Continuing Education Needs and Opportunities: A survey

Open Journal of Occupational Therapy, 2013
Occupational therapists (OTs) are expected to maintain up-to-date knowledge and clinical competence by engaging in continuing professional education (CPE).
Husny Amerih Ph.D., OTR, ATP
doaj  

Characterizing Runs of Homozygosity and Inbreeding in American Mink Using SNP Data and Pedigree Information

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Inbreeding increases the likelihood of deleterious recessive alleles becoming homozygous and consequently affecting economically important traits. Runs of homozygosity (ROH), the continuous homozygous segments of the genome and the higher than expected homozygosity (HOM) are genomic indicators of inbreeding, quantified as FROH and FHOM ...
Persia Carol Thapa, Duy Ngoc Do, Pourya Davoudi, Ghader Manafiazar, Younes Miar   +4 more
wiley   +1 more source

Incidence and relative risk of negative outcomes of psychological interventions for pediatric posttraumatic stress disorder: a systematic review and meta‐analysis of randomized controlled trials

Journal of Child Psychology and Psychiatry, EarlyView.
Background Negative outcomes of psychological treatments for pediatric posttraumatic stress disorder (PTSD) have been underresearched. Although reporting has increased over the years, a comprehensive systematic review and meta‐analysis is lacking. Methods We conducted a preregistered systematic review and meta‐analysis (PROSPERO ID: CRD42020206290) and
Thole H. Hoppen, Sophie Schlüter, Marielle Placzek, Anna S. Lindemann, Ahlke Kip, Pascal Schlechter, Richard Meiser‐Stedman, Nexhmedin Morina   +7 more
wiley   +1 more source

Comparison of quality and flavor between on-tree storage and cold storage of Satsuma ‘Youliang’

Food Chemistry: Molecular Sciences
This study investigates the effects of on-tree storage (OTS) on the quality and flavor of Satsuma ‘Youliang’ compared with cold storage (COS). Fruit quality was assessed based on sugar-acid ratio and juice flavor profiles. Comparative analysis revealed a
Chenyu Wang, Jintao Wang, Chungeng Hong, Gang Chen, Wanying Ge, Yongxin Li, Huqing Yang   +6 more
doaj   +1 more source

Clinical Evaluation of CAD/CAM All‐Ceramic Crowns: A Randomized Controlled Study Comparing Lithium Disilicate and Lithium Aluminosilicate

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective To compare the marginal and internal adaptation and to evaluate the clinical performance and patient satisfaction of CAD/CAM‐fabricated all‐ceramic crowns produced from lithium disilicate (LDS) and lithium disilicate–reinforced lithium aluminosilicate (LAS) over a 24‐month follow‐up period.
Sinem Ok Tokaç, Kübra Yıldız Domaniç, Yılmaz Umut Aslan, Yasemin Özkan   +3 more
wiley   +1 more source

A systems engineering framework for the design of bioprocess operator training simulators

E3S Web of Conferences, 2019
Operator training simulators (OTS) are widely used in several industries including chemical processing, oil and gas, medicine, aircraft and nuclear facilities. However, developing a biorefinery OTS is a complex engineering design activity that requires a
Isimite Joseph, Baganz Frank, Hass Volker   +2 more
doaj   +1 more source

Preventing Constipation in People Living With Dementia: Co‐Design of a Non‐Pharmacological Care Bundle for Residential Aged Care

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim(s) To develop a care‐bundle of non‐pharmacological strategies with the potential to prevent constipation in people with dementia in Residential Aged Care (RAC). Design Mixed‐methods intervention development study using Modified Delphi and co‐design, informed by evidence, current constipation prevention practices and stakeholder ...
Linda Schnitker, Zoe Selby, Mili Dhir, Jeena Wagle, Yvonne Feeley, Dominique Myers, Rekha Singh, Deepa Sriram, Kate Mcleod, Fleur O'Keefe, Kath Paine, Claudia Meyer, Jane Phillips, Judy A. Lowthian   +13 more
wiley   +1 more source

Central Asia and Turkey: The Quest for Integration Models

Евразийская интеграция: экономика, право, политика
Aim . To identify the specific features of the system of relations between Turkey and Central Asian states at the present stage. Tasks. The main tasks were to identify the basic aspects of building a “common Turkic identity”, review the main projects of ...
Maria A. Kolesnikova
doaj