Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann +25 more
wiley +1 more source
Az ott szokatlan szerepei. Igekötő, diskurzuspartikula [PDF]
Az ott határozószó redundáns használata (= ahol a mondatban szerepel a nominális helymegjelölés is, vö. Éva ott állt a kapuban versus Éva a kapuban állt) összevethető a hasonló irányhatározós szerkezetekkel (Éva belépett a szobába).
Kocsány, Piroska
doaj +1 more source
Vanishing of the upper critical field in Bi_2Sr_2CaCu_2O_{8+\delta} from Landau-Ott scaling [PDF]
We apply Landau-Ott scaling to the reversible magnetization data of Bi$_2$Sr$_2$CaCu$_2$O$_{8+\delta}$ published by Y. Wang et al. [\emph{Phys. Rev. Lett.
A. A. Abrikosov +4 more
core +1 more source
Una mirada epistemológica sobre el costo de los nuevos bienes de capital
El mundo se encuentra ante una nueva etapa de la economía sustentada en grandes infraestructuras globales. Esta infraestructura está compuesta por bienes de capital con componentes virtuales y físicos que deben poder ser entendidos desde el marco ...
Juan Francisco Rodríguez Brites
doaj
Aim. To create collection of plasma and leukocyte blood samples from pregnant women to improve methods of non-invasive prenatal testing, as well as to search for deoxyribonucleic acid markers and study the molecular mechanisms of gestational ...
E. S. Vashukova +9 more
doaj +1 more source
Average activity of excitatory and inhibitory neural populations [PDF]
We develop an extension of the Ott-Antonsen method [E. Ott and T. M. Antonsen, Chaos 18(3), 037113 (2008)] that allows obtaining the mean activity (spiking rate) of a population of excitable units.
Mindlin, Bernardo Gabriel +1 more
core +2 more sources
Description of the male of Cybaeodamus lycosoides (Nicolet), with new distributional data for C. meridionalis Lise, Ott & Rodrigues (Araneae, Zodariidae) [PDF]
El macho de la araña zodariida chilena Cybaeodamus lycosoides (Nicolet, 1849) se describe e ilustra por primera vez. Se aportan nuevos registros para esta especie, incluyendo los primeros para Perú, como también nuevas localidades de Argentina para C ...
Andía, Juan Manuel +1 more
core +1 more source
A STUDY ON THE CONSUMPTION PATTERN AND VIEWER EXPERIENCE OF OTT PLATFORMS WITH SPECIAL REFERENCE TO ERNAKULAM CITY [PDF]
Over-The-Top (OTT) streaming services distribute online audio-visual content, including music. These platforms don't make use of the typical cable or satellite feeds as traditional television does.
T J Rejo , V. Ramadevi
doaj +1 more source
The Swallowing Characteristics of Thickeners, Jellies and Yoghurt Observed Using an In Vitro Model [PDF]
© The Author(s) 2019 Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in ...
Cook, Michael T. +5 more
core +3 more sources
Extended Fused Carbazole‐BODIPY, High Brightness NIR Organic Dyes
Highly fused boron‐dipyrromethene (BODIPY) with a strong donor group has been synthesized, and their photophysical behaviors fully characterized. They exhibit outstanding brightness for fluorophores emitting in the NIR region. Water‐soluble nanoparticles filled with one of these dyes demonstrate high efficiency as the NIR II visualization agent ...
Fabien Ceugniet +9 more
wiley +2 more sources

