Results 211 to 220 of about 37,475 (253)
Contribution of glial inwardly rectifying potassium (Kir) channels to potassium buffering in insect neural systems. [PDF]
iScienceChen R, Li Z, Johnson A, Swale DR.
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Effect of Ouabain on the Cholinergic System in Rat Retinal Cell Cultures
Michelle Cristina Munhoz Di Flora [UNESP] Oliveira
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Endogenous Ouabain Is Not Ouabain
Hypertension, 2014The concept of a circulating digitalis-like inhibitor of the sodium pump, Na+, K+-ATPase, evolved from studies performed in the 1960s. De Wardener et al1 addressed the question of whether a small increase in the glomerular filtration rate together with changes in the concentration of the more recently discovered hormone aldosterone could explain the ...
Lynley K, Lewis +5 more
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Is the Circulating Ouabain-like Compound Ouabain?
American Journal of Hypertension, 1994The evidence is very strong for a circulating inhibitor of the sodium, potassium ATPase in volume-expanded hypertension. Recently, this inhibitor was isolated from human plasma and identified as ouabain. We are reporting our results using a very specific and sensitive immunoassay for ouabain with which we were unable to detect or able to detect only ...
E P, Gomez-Sanchez +4 more
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Cell Calcium, 2020
In this brief review we discuss some aspects of the Na+ pump and its roles in mediating the effects of ouabain and endogenous ouabain (EO): i) in regulating the cytosolic Ca2+ concentration ([Ca2+]CYT) via Na/Ca exchange (NCX), and ii) in activating a number of protein kinase (PK) signaling cascades that control a myriad of cell functions. Importantly,
Mordecai P. Blaustein, John M. Hamlyn
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In this brief review we discuss some aspects of the Na+ pump and its roles in mediating the effects of ouabain and endogenous ouabain (EO): i) in regulating the cytosolic Ca2+ concentration ([Ca2+]CYT) via Na/Ca exchange (NCX), and ii) in activating a number of protein kinase (PK) signaling cascades that control a myriad of cell functions. Importantly,
Mordecai P. Blaustein, John M. Hamlyn
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Current Opinion in Nephrology and Hypertension, 1998
Accumulated evidence has suggested that several sodium pump inhibitors, similar to cardiotonic steroids, are present in the human body. Ouabain-like factor, the most appealing candidate, has been found to be increased with high sodium intake and hypervolaemia, and in essential hypertension, mineralocorticoid hypertension, and pregnancy-induced ...
A, Goto, K, Yamada
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Accumulated evidence has suggested that several sodium pump inhibitors, similar to cardiotonic steroids, are present in the human body. Ouabain-like factor, the most appealing candidate, has been found to be increased with high sodium intake and hypervolaemia, and in essential hypertension, mineralocorticoid hypertension, and pregnancy-induced ...
A, Goto, K, Yamada
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Ouabain Hypoglycemia: Insulin Mediation
Science, 1968The fall in blood sugar occurring during infusion of ouabain (1 microgram per kilogram per minute for a 60-minute period) in dogs is accompanied by an increased uptake of glucose and potassium by the liver. Concurrently, plasma insulin in the portal blood increases significantly.
L, Triner, P, Killian, G G, Nahas
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Ouabain-induced cell signaling
Frontiers in Bioscience, 2005When endogenous ouabain was first isolated from human plasma in 1991, many expressed doubts that such a compound could be endogenous to humans because of its unusual structure, its unknown synthesis, and its unidentified site of origin. Furthermore, the relevance of human ouabain was questioned because of its apparently low (< or =nmol/L) circulating ...
Steven, Harwood, Muhammad M, Yaqoob
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