Results 221 to 230 of about 37,475 (253)

Mechanisms of ouabain toxicity

The FASEB Journal, 2003
ABSTRACT The suggested involvement of ouabain in hypertension raised the need for a better understanding of its cellular action, but the mechanisms of ouabain toxicity are only now being uncovered. In the present study, we show that reduced glutathione (GSH) protected ouabain‐sensitive (OS) cells from ouabain ...
Raphael C, Valente, Luiz S, Capella, Robson Q, Monteiro, Vivian M, Rumjanek, Aníbal G, Lopes, Márcia A M, Capella   +5 more
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Endogenous Ouabain in Ménière's Disease

Otology & Neurotology, 2010
Endogenous Ouabain (EO) has been demonstrated to modulate the activity of Na+, K+ -ATPase. Our purpose was to measure plasma levels of EO in Ménière's Disease (MD) subjects as a possible predisposing factor to developing and maintaining hydrops.Case-control study.University hospital.Thirty-nine MD subjects and 29 controls with a lifetime negative ...
Teggi Roberto, Zagato Laura, Carpini Simona Delli, Messaggio Elisabetta, Casamassima Nunzia, Lanzani Chiara, MANUNTA , PAOLO, BUSSI , MARIO   +7 more
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Effect of ouabain on Sindbis virus replication in ouabain-sensitive and ouabain-resistant Aedes albopictus cells (Singh)

Virology, 1978
Abstract The effects of ouabain on Sindbis virus replication in cloned sublines of ouabain-sensitive (B 1 C 4 ) and -resistant (Oua 5 ) Aedes albopictus cells have been studied. The addition of ouabain (0.1 m M ) to B 1 C 4 cells 1 hr after infection reduced the yield of infectious virus 500-fold.
S J, Mento, V, Stollar
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Role of Ouabain-Like Factors in Hypertension

Journal of Cardiovascular Pharmacology, 1993
Several reports suggest the presence of sodium-potassium pump inhibitor in plasma and various tissues, particularly during volume-expanded state and low-renin hypertension. It has been hypothesized that by inhibiting the cardiovascular muscle-cell Na(+)-K+ pump, this inhibitor can constrict blood vessels, enhance vasoconstriction, and increase cardiac ...
YUAN C, MANUNTA , PAOLO, CHEN S, HANLYN JM, HADDY FJ, PAMNANI MB   +5 more
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Apical ouabain-sensitive and ouabain-insensitive ATPases in rat colonic epithelium

Acta Histochemica, 2002
Active resorption of potassium ions in the colon is mediated by ouabain-sensitive and ouabain-insensitive H,K-ATPases localized in the apical membrane of colonic enterocytes (colonocytes). The present study was performed to investigate distribution patterns of apical ATPases using catalytic histochemistry and immunohistochemistry.
Radomíra, Vagnerová, Zdenka, Zemanová, Jirí, Pácha, Jaroslava, Smídová   +3 more
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Ouabain Antagonists as Antihypertensive Agents

Current Pharmaceutical Design, 2005
The evidence that high levels of endogenous ouabain (EO), a closely related isomer of ouabain, are implicated in human hypertension and cardiac hypertrophy and failure stimulated the pharmacological research for developing novel anti-hypertensive agents active as ouabain antagonists.
M, Ferrandi, P, Barassi, I, Molinari, L, Torielli, G, Tripodi, E, Minotti, G, Bianchi, P, Ferrari   +7 more
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Relationship between ouabain and asthenozoospermia

Journal of Huazhong University of Science and Technology [Medical Sciences], 2014
A growing number of researches have shown that ouabain can regulate mammalian sperm function and male reproduction by modulating the sperm motility, capacitation and acrosome reaction in vitro. This study further examined the relationship between ouabain and asthenozoospermia.
Yi-Hong, Yang, Yan, Wan, Huan, Lou, Ting, Xue, Ping, Su   +4 more
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Erythrocyte Ouabain Binding in Dementia

Gerontology, 1983
Age-matched patients attending a geriatric psychiatry day hospital, one group with Alzheimer's dementia and another with functional illness, were studied and compared with similar inpatient groups. Erythrocyte ouabain binding was assayed and Clifton ratings completed.
A, McHarg, G J, Naylor, B R, Ballinger
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Ouabain as a Mammalian Hormone

Annals of the New York Academy of Sciences, 2003
Abstract: Endogenous ouabain changes rapidly in humans and dogs upon physical exercise and is under the control of epinephrine and angiotensin II. Hence, the steroid acts as a rapidly acting hormone. A search for a specific binding globulin for cardiac glycosides in bovine plasma resulted in the identification of the d allotype of the μ chain of IgM ...
Wilhelm, Schoner, Natali, Bauer, Jochen, Müller-Ehmsen, Ulrike, Krämer, Njde, Hambarchian, Robert, Schwinger, Hans, Moeller, Holger, Kost, Christine, Weitkamp, Thomas, Schweitzer, Ulrike, Kirch, Horst, Neu, Ernst-Güngther, Grünbaum   +12 more
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Erythrocyte sodium pump stimulation by ouabain and an endogenous ouabain‐like factor

Cell Biochemistry and Function, 2006
AbstractCardiac glycosides inhibit the sodium pump. However, some studies suggest that nanomolar ouabain concentrations can stimulate the activity of the sodium pump.In this study, using the Na+/K+‐ATPase of human erythrocytes, we compared the effect of digoxin, ouabain and an ouabain like‐factor (OLF), on 86Rb uptake.Ouabain concentrations below 10−9 ...
Balzan S, D'Urso G, Nicolini G, Forini F, Pellegrino M, Montali U   +5 more
openaire   +3 more sources