Results 71 to 80 of about 15,069 (219)

The association of extreme environmental heat with incidence and outcomes of out-of-hospital cardiac arrest in British Columbia: A time series analysis

open access: yesResuscitation Plus
Background: The impact of extreme heat on out-of-hospital cardiac arrest (OHCA) incidence and outcomes is under-studied. We investigated OHCA incidence and outcomes over increasing temperatures.
Laiba Khan   +9 more
doaj   +1 more source

Trackable Tolerogenic Macrophages Integrate PD‐L1 and Rapamycin Signaling to Suppress Alloimmune Responses in Transplantation

open access: yesAdvanced Science, EarlyView.
We developed a macrophage‐based therapeutic platform, termed trackable tolerogenic macrophages (TTM), for dual‐function immunomodulation and visualization in vivo. TTM cells were engineered to overexpress PD‐L1, incorporate bioorthogonal cell surface tags, and load rapamycin for sustained release.
Yihui Wang   +14 more
wiley   +1 more source

Underlying Cause of Out‐of‐Hospital Cardiac Arrests in Japan in Survivors Versus Nonsurvivors

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The causes underlying out‐of‐hospital cardiac arrest (OHCA) are rarely investigated. This study aimed to investigate causes of OHCA in CRITICAL (Comprehensive Registry of In‐Hospital Intensive Care for OHCA Survival), a multicenter OHCA ...
Satoshi Yoshimura   +28 more
doaj   +1 more source

Mechanical circulatory support for refractory out-of-hospital cardiac arrest: a nationwide multicentre study [PDF]

open access: bronze, 2021
S R Moerk   +14 more
openalex   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

open access: yesAdvanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu   +11 more
wiley   +1 more source

Epidemiology and outcomes of out-of-hospital cardiac arrests at sport and recreational events in England, 2015–2022

open access: yesResuscitation Plus
Background: Previous studies suggest favourable outcomes for patients experiencing exercise-related out-of-hospital cardiac arrest (OHCA). This study aimed to examine the characteristics and outcomes of OHCAs occurring at sports and recreational events ...
Helen Winterburn   +6 more
doaj   +1 more source

Out of hospital cardiac arrest: when to resuscitate

open access: yesThe Pan African Medical Journal, 2019
INTRODUCTION: This study explores why resuscitation is withheld when mobile emergency medical team arrive at the scene of a cardiac arrest.
Saida Zelfani   +3 more
doaj   +1 more source

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

open access: yesAdvanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza   +19 more
wiley   +1 more source

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