PRDM16 Reduces Cellular Senescence by Upregulating GSTM1
Advanced Science, EarlyView.Cellular senescence drives aging and aging‐related organ disorders, yet PRDM16's role remains unexplored. This work uncovers that PRDM16 decreases significantly in aged organs, while its loss accelerates cellular senescence and aging‐related organ injury.
Qian Yuan +7 more
wiley +1 more source
A Man With Out-of-Hospital Cardiac Arrest [PDF]
Annals of Emergency Medicine, 2021 Sheng-En Chu +9 more
openaire +3 more sources
Cardiac arrest recognition and telephone CPR by emergency medical dispatchers [PDF]
, 2017 Emergency Medical Service (EMS) systems annually encounters about 275 000 out-of-hospital cardiac arrest (OHCA) patients in Europe and approximately 420,000 cases in the United States.1 Survival rates have been reported to be poor with approximately
Attard Biancardi, Mark Anthony +2 more
core
Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism
Advanced Science, EarlyView.Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang +4 more
wiley +1 more source
Mechanical chest-compression devices: current and future roles [PDF]
, 2010 Purpose of review: It is recognised that the quality of CPR is an important predictor of outcome from cardiac arrest yet studies consistently demonstrate that the quality of CPR performed in real life is frequently sub-optimal.
Brace, Samantha J. +2 more
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Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis
Advanced Science, EarlyView.The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li +12 more
wiley +1 more source
Advanced Science, EarlyView.The restoration of blood flow following surgical decompression for degenerative cervical myelopathy (DCM) significantly contributes to the amelioration of neurological deficits. This study identifies AGAPIR, an angiogenesis‐associated PIWI‐interacting RNA, enhances angiogenesis and motor function recovery post‐spinal cord decompression in a mouse model
Yongheng Xie +8 more
wiley +1 more source
Duration of In-hospital Advanced Cardiac Life Support for Out-of-hospital Cardiac Arrest [PDF]
, 2016 博士(医学) 乙第2904号(主論文の要旨、要約、本文)著者名:諸井 隆一・武田 宗和・島本 周治・並木 みずほ・矢口 有乃,タイトル:院外心肺停止症例に対する病着後二次救命処置施行時間に関する検討,掲載誌:東京女子医科大学雑誌(0040-9022),巻・頁・年:85巻5号p.177-185(2015)博士(医学 ...
諸井 隆一
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Advanced Science, EarlyView.Mesenchymal stromal cells (MSC) are considered a promising alternative for neuropathic pain (NP) treatment, but underlying mechanisms remain elusive. Huang et al. illustrate that a Npy2r sensory neuron‐related lung–brain axis contributes to MSC analgesia.
Jing Huang +25 more
wiley +1 more source
Recommended guidelines for uniform reporting of data from out-of-hospital cardiac arrest: the Utstein Style. A statement for health professionals from a task force of the American Heart Association, the European Resuscitation Council, the Heart and Stroke Foundation of Canada, and the Australian Resuscitation Council. [PDF]
, 1991 Richard O. Cummins +9 more
openalex +1 more source