Results 61 to 70 of about 168,171,873 (264)

Microgels Enable iPSCs to Assemble, Expand, and Differentiate Into Organoids—From Sizable to High‐Throughput

Advanced Materials, EarlyView.
A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen, Matthias Mork, Ramin Nasehi, Vasudha Turuvekere Krishnamurthy, Kira Zeevaert, Aaron Babendreyer, Jacopo Di Russo, Wolfgang Wagner, Laura De Laporte   +8 more
wiley   +1 more source

Risk factors and outcome of extracorporeal cardiopulmonary resuscitation patients with out-of-hospital cardiac arrest and in-hospital cardiac arrest: a nationwide prospective and observational study of 939 hospitals in China

BMC Emergency Medicine
Background Sudden cardiac arrest represents a global health challenge characterized by high mortality and morbidity rates. Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly considered as an effective treatment for cardiac arrest ...
Di Shi, Bo Li, Wei Pan, Fuping Guo, Hui Jiang, Liu Chengxi, Huadong Zhu, Jihai Liu, Jieqing Chen, Liang Zong, Xiao Song, Chen Lin, Xin Ding, Xiang Zhou, Chang Yin, Bin Du, on behalf of the China National Critical Care Quality Control Center-the ECMO quality improvement action (EQIA) study   +16 more
doaj   +1 more source

Microfluidic Droplet Plate Preserving Single Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Morphology and Function

Advanced Materials Technologies, EarlyView.
We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang, Rachel P. White, Yashasvi Tharani, Michael A. Finocchiaro, Leona M. Ripple, Maksymilian Prondzynski, Tania Konry, Vassilios J. Bezzerides   +7 more
wiley   +1 more source

Methodology for creating a novel cardiac arrest registry using the Trinetx electronic health record database

Resuscitation Plus
Background: Care in the hospital, post-arrest care, is a crucial component of out-of-hospital cardiac arrest (OHCA) management, but current OHCA databases contain limited post-arrest care data. To address this, we present the methodology for assembling a
Ryan Huebinger, Ryan A. Coute, Larissa Myaskovsky, Cameron Crandall, Ethan Abbott, Keith E. Kocher, Aditya C Shekhar, Benjamin S. Abella   +7 more
doaj   +1 more source

Real‐Time Holographic Feedback via Mixed Reality Sensorized Laryngoscope Training System Enhances Pediatric Intubation Training

Advanced Robotics Research, EarlyView.
We proposed a Mixed Reality Sensorized Laryngoscope Training System to provide real‐time holographic torque feedback during pediatric endotracheal intubation simulation. Visualization formats are evaluated to reduce tracking error and visual demand.
Jiaqi Li, Ryman Hashem, Ningzhe Hou, Perla Maiolino, Louis Halamek, Liang He   +5 more
wiley   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

First automated detection of a cardiac arrest using a commercially available smartwatch: a case report

Resuscitation Plus
Background: Automated cardiac arrest detection aims to shorten the time between arrest onset and emergency medical services activation, thereby reducing the number of unwitnessed out-of-hospital cardiac arrests (OHCA) and shortening time to treatment in ...
Wisse M.F. van den Beuken, Pieter R. Tuinman, Beat Nideröst, Sebastiaan A. Goossen, Hans van Schuppen, Stephan A. Loer, Lothar A. Schwarte, Patrick Schober   +7 more
doaj   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Cardiac arrest after STEMI and importance of early cardiopulmonary resuscitation in non hospital setting-time is life/myocard [PDF]

ABC: časopis urgentne medicine, 2016
INTRODUCTION: In 23 % of cases, sudden cardiac death can be the first manifestation of coronary artery disease. In these cases pulseless VT and VF are the most common causes for cardiac arrest.
Niković Vuk, Kojić Dejan, Milenković Dušan, Bulajić Ranka, Hodžić Edvin, Boljević Aleksandra   +5 more
doaj  

Characteristics of out of hospital cardiac arrest in the United Arab Emirates

Heart Views, 2019
Background: Out of hospital cardiac arrest is one of the leading causes of death globally. This study aimed to identify the characteristics of out of hospital cardiac arrest patients who were attended and treated by the National Ambulance crew.
Saad Essa Alqahtani, Ahmed Saleh Alhajeri, Ayman Adel Ahmed, Sahar Yousef Mashal   +3 more
doaj   +1 more source