Results 31 to 40 of about 193,201 (262)

Clinical investigation of an outbreak of alveolitis and asthma in a car engine manufacturing plant [PDF]

open access: yes, 2007
Background Exposure to metal working fluid (MWF) has been associated with outbreaks of EAA in the US, with bacterial contamination of MWF being a possible cause, but was uncommon in the UK.
Burge, P.S.   +19 more
core   +1 more source

Viral Infection‐Inspired Autonomous Detection of Fusion‐Competent Viruses for Screening and Environmental Surveillance

open access: yesAdvanced Materials, EarlyView.
Inspired by viral entry mechanisms, the FUSION assay enables autonomous detection of respiratory viruses via membrane fusion–triggered CRISPR‐Cas13a activation. VEACON selectively fuses with fusion‐competent viruses, triggering fluorescence within confined vesicles.
Jae Chul Park   +15 more
wiley   +1 more source

Sensitive and Spatially‐Resolved Electrochemiluminescence via Micropatterning

open access: yesAdvanced Materials Interfaces, EarlyView.
The use of a simple silica nanoparticle surface coating and patterning process can transform ordinary gold electrodes into multiplexed ECL sensing electrodes. Through spatially confined droplet formation and local ECL emission, it is possible to perform multiple analyses simultaneously from individual locations as well as intensify the ECL signal by as
Yuliang Shao   +12 more
wiley   +1 more source

Assessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling

open access: yesNature Communications, 2017
Artemether lumefantrine is widely used for the treatment of uncomplicated malaria. The impact of imperfect patient adherence to the six-dose regimen is hard to assess.
Joseph D. Challenger   +3 more
doaj   +1 more source

A novel model fitted to multiple life stages of malaria for assessing efficacy of transmission-blocking interventions

open access: yesMalaria Journal, 2017
Background Transmission-blocking interventions (TBIs) aim to eliminate malaria by reducing transmission of the parasite between the host and the invertebrate vector.
Ellie Sherrard-Smith   +7 more
doaj   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

open access: yesAdvanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao   +11 more
wiley   +1 more source

Identification and Expression Analysis of the Cytochrome P450 Genes in Phyllotreta striolata and CYP6TH1/CYP6TH2 in the Involvement of Pyridaben Tolerance

open access: yesInsects
The striped flea beetle, Phyllotreta striolata, is a worldwide pest that causes severe damage to cruciferous crops. Pyridaben, an inhibitor of mitochondrial complex I, has been widely used for the control of P. striolata.
Yongqin Zhu   +6 more
doaj   +1 more source

A retrospective review of rabies post-exposure prophylaxis queries, South Africa, 2016–2019

open access: yesSouthern African Journal of Infectious Diseases, 2022
Background: The National Institute for Communicable Diseases (NICDs) of South Africa (SA) provides technical support to healthcare workers (HCWs) with regard to infectious diseases through the NICD clinician hotline.
Trisha A. Whitbread   +7 more
doaj   +1 more source

AN "INFLUENZA" OUTBREAK. [PDF]

open access: yesThe Lancet, 1918
n ...
openaire   +1 more source

Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse

open access: yesAdvanced Science, EarlyView.
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang   +7 more
wiley   +1 more source

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