Results 91 to 100 of about 32,094 (189)

Inbred or Outbred? Genetic diversity in laboratory rodent colonies

G3 Genes|Genomes|Genetics, 2017
ABSTRACT Non-model rodents are widely used as subjects for both basic and applied biological research, but the genetic diversity of the study individuals is rarely quantified. University-housed colonies tend to be small and subject to founder effects and genetic drift and so may be highly inbred or show substantial ...
Brekke, Thomas D., Steele, Katherine A., Mulley, John F.   +2 more
openaire   +3 more sources

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, Volume 16, Issue 7, Page 1244-1258, July 2026.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Pengaruh Outer Membrane Protein Helicobacter Pylori terhadap Perubahan Histopatologi Mukosa Lambung dan S-IgA pada Mus musculus Outbred Balb/C

Journal of Experimental Life Science, 2011
Helicobacter pylori (H. pylori) merupakan bakteri penyebab inflamasi mukosa lambung. Faktor virulensi bakteri berperan pada patogenesis penyakit infeksi oleh bakteri yang pada umumnya dapat merangsang sistem imun.
Yuniati Yuniati, Harijono Achmad, Sumarno Sumarno   +2 more
doaj   +1 more source

Low‐frequency electroacupuncture attenuates insulin resistance in a rat model of diet‐induced maternal obesity

Pregnancy, Volume 2, Issue 4, July 2026.
Abstract Introduction Maternal obesity is highly prevalent worldwide, conferring elevated risks of maternal/fetal complications and adult‐onset disease in offspring. Obesity and pregnancy are both states of insulin resistance. Percutaneous electrical stimulation of skeletal muscle, better known as electroacupuncture (EA), mitigates insulin resistance ...
David J. Carr, Elizabeth Kelley, Morgan Sekhon, Megan Kawasaki, Keara McElroy‐Yaggy, R. Chris Skinner, Paul D. Taylor, Anna L. David, Elisabet Stener‐Victorin, Thomas L. Jetton   +9 more
wiley   +1 more source

De Novo Genome Assemblies of Four Rainbow Trout Genetic Lines Reveal Structural Variants in Pursuit of a Pangenome Reference

Molecular Ecology Resources, Volume 26, Issue 5, July 2026.
ABSTRACT Rainbow trout (Oncorhynchus mykiss) exhibit extensive genomic diversity shaped by domestication, life history and geographic origin. To advance the development of a comprehensive pangenome reference, we present new de novo genome assemblies of two genetically and ecologically distinct lines: Whale Rock (WR; wild, landlocked, Central California)
Ali Ali, Geoffrey C. Waldbieser, Ramey C. Youngblood, Paul A. Wheeler, Brian E. Scheffler, Stuart Willis, Shawn R. Narum, Gary H. Thorgaard, Mohamed Salem, Yniv Palti   +9 more
wiley   +1 more source

Incorporating Population Genomic Perspectives Into Kelp Conservation and Aquaculture in the Pacific Northwest

Evolutionary Applications, Volume 19, Issue 7, July 2026.
ABSTRACT Recent kelp forest declines and growth in the kelp aquaculture industry have fueled increasing interest in ecological and evolutionary research on kelp forests, including kelp population genomics. Although many kelp management activities have inherent genetic and evolutionary implications, kelp management in the Pacific Northwest (PNW) of ...
Jordan B. Bemmels, Gregory L. Owens
wiley   +1 more source

Immunogenicity of a Multi‐Epitope Influenza Composite Peptide Vaccine Targeting Human, Swine, and Avian Viruses: Advancing Pandemic Preparedness

Influenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.
ABSTRACT Background The emergence of novel reassortant influenza A virus strains and zoonotic transmission to the human population is a critical factor in the development of a global pandemic, as exemplified by the 2009 swine flu pandemic and the ongoing threat of an H5N1 avian flu pandemic.
Nimisha Rikhi, Clara J. Sei, Kellie A. Fraser, Kevin Muema, Aba Assiaw‐Dufu, Richard F. Schuman, Gerald W. Fischer   +6 more
wiley   +1 more source

Strain-Dependent Gene Expression during Mouse Embryonic Palate Development

Journal of Developmental Biology, 2015
The effect of strain background on gene function in growth and development has been well documented. However, it has not been extensively reported whether the strain background affects the gene expression pattern.
Jiu-Zhen Jin, Jixiang Ding
doaj   +1 more source

Pubertal development and hypothalamic–pituitary–gonadal axis are altered in male mice lacking Mecp2

Journal of Neuroendocrinology, Volume 38, Issue 7, July 2026.
Abstract Mutations in the MECP2 gene, encoding the epigenetic reader Methyl‐CpG binding protein 2, are the main cause of Rett syndrome, a rare neurodevelopmental disorder. Besides severe symptoms such as profound intellectual disability, loss of speech and motor skills, and epilepsy, loss of function of MECP2 has been associated with pubertal ...
Ana Martín‐Sánchez, Daniela Jiménez‐Díaz, Rafael Esteve‐Pérez, Alexandru Vasile‐Tudorache, Jordan E. Read, Sasha R. Howard, Carmen Agustín‐Pavón   +6 more
wiley   +1 more source

The Complex Relation of Branched‐Chain Amino Acids and Inflammation in the Obesity and Diabetes Context

Obesity Reviews, Volume 27, Issue 7, July 2026.
ABSTRACT In a scenario with increasing cases of obesity and diabetes worldwide, branched‐chain amino acids (BCAA) metabolism has become an important factor in the understanding of these pathologies. More recently, its chronic high plasma levels have been postulated, alongside glucose, inflammatory factors, and other molecules, as an important ...
Bernardo Starling‐Soares, Monique Macedo Coelho, Bruna Guerra Campolina, Camila Kümmel Duarte, Tatiani Uceli Maioli   +4 more
wiley   +1 more source