Results 151 to 160 of about 909,126 (261)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

The effectiveness of a foot-care education program based on multi-theory model in diabetic patients with risk of foot ulceration: A randomized controlled trial protocol. [PDF]

PLoS One
Xu H, Wu C, Zhang L, Ju Y, Chen J, Hu Q, Qiu S.   +6 more
europepmc   +1 more source

Outcome based Education(smartOBE)

International Research Journal of Modernization in Engineering Technology and Science, 2023
openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Optimizing diabetes self-care in patients with limited health literacy: a randomized controlled trial (RCT) of SCT-based education with and without an AI-designed photo-novel. [PDF]

BMC Health Serv Res
Chekav T, Javadzade H, Mahmoodi M, Reisi M.   +3 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Simulation-based training: Assessment of impact on medical students' performance, confidence in CPR, and patient outcomes - A single-center study. [PDF]

J Educ Health Promot
Fathima JR, Kumar KS, Aarthi T, Gaayathri K, Raja S.   +4 more
europepmc   +1 more source

Towards Outcome-based Education [PDF]

Higher Education for the Future, 2018
openaire   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Effectiveness of AI-enhanced virtual patients for psychiatric interview training in health professions education: a meta-analysis. [PDF]

Front Med (Lausanne)
Kilincel S, Bulut F, Goksel P, Usta MB, Mutluer T, Kilincel O.   +5 more
europepmc   +1 more source