Results 141 to 150 of about 10,060,126 (337)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Ataxia-telangiectasia: immunologic profile and clinical outcome [PDF]

, 2015
Clarissa De Lima Honório Dumas, Fabíola Scancetti Tavares, Hermínio De Paula Ramos Netto, Vanessa Silva Pereira Campos, Cláudia França Cavalcante Valente, Luciana Lilian Dias Pereira   +5 more
openalex   +1 more source

Comorbidities Burden and Implementation of the Treat–to–Target Strategy in Predicting Real-World Patient Outcomes in Spondyloarthritides

, 2023
Irini Flouri, Argyro Repa, Nestor Avgoustidis, Sofia Pitsigavdaki, K. Pateromichelaki, Eleni Marolachaki, Maria Terizaki, Myrto Nikoloudaki, Anastasios Eskitzis, Eleni Kalogiannaki   +9 more
openalex   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Erratum to: “Like a lots happened with my whole childhood”: violence, trauma, and addiction in pregnant and postpartum women from Vancouver’s Downtown Eastside

Harm Reduction Journal, 2017
Iris Torchalla, Isabelle Aube Linden, Verena Strehlau, Erika K. Neilson, Michael Krausz   +4 more
doaj   +1 more source

PPA1 regulates tumor malignant potential and clinical outcome of colon adenocarcinoma through JNK pathways

, 2017
Ping Wang, Yi Zhou, Qi Mei, Jing Zhao, Liu Huang, Qiang Fu   +5 more
openalex   +2 more sources

Drug prescription clusters in the UK Biobank: An assessment of drug-drug interactions and patient outcomes in a large patient cohort [PDF]

, 2022
Kyriakos Schwarz, Daniel Trejo Baños, Giulia Rathmes, Michael Krauthammer   +3 more
openalex   +1 more source

Predicting outcome following colorectal cancer surgery using Colorectal Biochemical and Haematological Outcome Model (Colorectal BHOM) [PDF]

, 2010
Farooq, N., Justin, T., Patterson, A., Prytherch, David, Tang, T., Walsh, S. R.   +5 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source