Results 161 to 170 of about 5,642,835 (279)

A continuous appraisal account of gratitude dynamics in social interactions. [PDF]

Commun Psychol
Hu J, Chen Y, Fu J, Liu Z, Zhang B, Hu Y, Gao X, Zhou X.   +7 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Effects of Orthotic Interventions on Pain, Balance, and Plantar Pressure in Flexible Flatfoot: A Systematic Review. [PDF]

J Foot Ankle Res
Choi T, Lee S, Choi W, Heo S.
europepmc   +1 more source

Removal of ineligible outcome cases reduces confounding

, 2018
Alexander M Walker,1 Sebastian Schneeweiss,2 Maral DerSarkissian,3 Mei Sheng Duh4 1World Health Information Science Consultants, Newton, MA, USA; 2Division of Pharmacoepidemiology, Department of Medicine, Brigham & Women’s Hospital and Harvard ...
Schneeweiss S, Duh MS, Walker AM, DerSarkissian M   +3 more
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Studying multiracial adolescents' racial self-categorization(s): Conceptual, methodological, and analytic recommendations. [PDF]

J Res Adolesc
Vezaldenos V, Grogan-Kaylor A, Rivas-Drake D.   +2 more
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Towards meaningful outcome measures for health economic evaluations in skin cancer : A decision matrix to guide transparent outcome selection in skin cancer health economic evaluations, supporting more informed decision-making. [PDF]

Cost Eff Resour Alloc
Meertens A, Annemans L, Verstraete F, Hoorens I, Verhaeghe N.   +4 more
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source