Results 171 to 180 of about 8,864,759 (285)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Clinical outcome following best medical management in acute stroke with a proximal isolated occlusion of the anterior cerebral artery: an international multicentre study. [PDF]

Eur Stroke J
Sabben C, Charbonneau F, Obadia M, Strambo D, Ong E, Heldner MR, Sibon I, Henon H, Mione G, Ter Schiphorst A, Sablot D, Rosso C, Agasse-Lafont T, Weisenburger Lile D, Papassin J, Moulin S, Triquenot-Bagan A, Legris L, Nehme N, Wolff V, Preterre C, Poll R, Béjot Y, Garnier P, Turc G, Mazighi M, Seners P.   +26 more
europepmc   +1 more source

Defining outcomes [PDF]

The Journal of Pediatrics, 2017
openaire   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Practical adaptability of a pre-hospital prognostic prediction model for patients following out-of-hospital cardiac arrest during the COVID-19 pandemic. [PDF]

BMJ Health Care Inform
Nishi M, Shikuma A, Uchino E, Matoba S, Naohiro Y, Tahara Y, Ikeda T.   +6 more
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

School food environment interventions for health and sustainability. [PDF]

Cochrane Database Syst Rev
Leibinger A, Holliday N, Klinger C, Tan X, Busert-Sebela L, Schwingshackl L, Rehfuess E, Durao S, von Philipsborn P.   +8 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Pre-operative activity level and a sport or recreation injury mechanism are associated with 2-year clinical outcome after proximal hamstring tendon repair. [PDF]

Arch Orthop Trauma Surg
Ebert J, Edwards P, Klinken S, Ricciardo B, Annear P, D'Alessandro P.   +5 more
europepmc   +1 more source

Magnesium intake and sleep symptoms: Findings from the Jiangsu Nutrition Cohort Study of Chinese adults

Journal of Nutrition & Intermediary Metabolism, 2017
Y. Cao, A.W. Taylor, R. Adams, S. Appleton, Z. Shi   +4 more
doaj   +1 more source