Causal mediation analysis for time-to-event outcomes on the Restricted Mean Survival Time scale: A pseudo-value approach. [PDF]
Chernofsky A, Lok JJ.
europepmc +1 more source
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
Association between erythritol and lung cancer: a two-sample Mendelian randomization study. [PDF]
Zhao Y, Zheng R, Luo K, Zhao H, Xiang W.
europepmc +1 more source
Relationship of Selected Prenatal Factors to Pregnancy Outcome and Congenital Anomalies
Sam Shapiro+2 more
openalex +2 more sources
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
Exploring factors influencing the consistent adoption of a post-stroke upper extremity outcome measure using Normalisation Process Theory. [PDF]
Choo SX+6 more
europepmc +1 more source
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien+7 more
wiley +1 more source
Reasons for Downgrading the Certainty of Evidence for Indirectness in Synthesis of Surgical Procedures for Patients With Fractures: A Meta-Research Analysis. [PDF]
Daou JP, Riera R, Pacheco RL.
europepmc +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source